- ￥3000 - 3999
- Abbiotec
- 美国
- 250631
- 2025年07月13日
- E, WB, IHC
- Rabbit
- H, M, R
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human EGFR.
- 亚型：
Rabbit Ig
- 形态：
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
- 保存条件：
Store at -20°C.
- 克隆性：
多克隆抗体
- 标记物：
见下方详细说明
- 适应物种：
H, M, R
- 宿主：
Rabbit
- 应用范围：
E, WB, IHC
- 浓度：
见详细说明信息
- 靶点：
EGFR
- 抗体英文名：
EGFR Antibody
- 抗体名：
EGFR Antibody
- 规格：
0.1 mg
EGFR Antibody产品详细介绍：
| 产品名称： | EGFR Antibody |
| 说明书： | http://www.abbiotec.com/antibodies/egfr-antibody【参考图片】 |
| 货号： | 250631 |
| 规格： | 0.1 mg |
| 产品描述： | Epidermal growth factor receptor (EGFR) is a receptor for EGF and for various members of the EGF family such as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. EGFR is involved in the control of cell growth and differentation. Binding of EGF to the receptor leads to dimerization, internalization of the EGF-receptor complex, induction of the tyrosine kinase activity, stimulation of cell DNA synthesis and cell proliferation. Defects in EGFR are associated with lung cancer. |
| 克隆类型： | Rabbit Polyclonal Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human EGFR. |
| 适用物种： | H, M, R |
| 应用范围： | E, WB, IHC |
| 应用说明： | E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:200-1:500 |
| 别名： | Epidermal growth factor receptor; receptor tyrosine-protein kinase ErbB-1; EGFR; ERBB1 |
| 形态： | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： | Deng J et al. 2013. Tumor Biology. 34(5):2791-800. PMID# 23824569. |
ABBIOTEC产品提供质量保证，提供完善的售后和技术支持，ABBIOTEC产品正品包装：
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文献和实验厦门大学的研究团队评估了 EGFR 作为三阴乳腺癌免疫治疗靶点的可能性，通过体内实验和体外实验的结果得出，EGFR CAR-T 细胞展示出对三阴乳腺癌细胞强大的杀伤效果和潜力，提出 EGFR CAR-T 可以进一步向临床方向进行探索，获益更多的患者。 三阴乳腺癌（TNBC）以其侵袭性强、复发快速和预后效果差而闻名。目前以嵌合抗原受体 T (CAR-T)细胞为首的免疫疗法，已经成为治疗 TNBC 的一种有效工具，而其中肿瘤特异性抗原的选择和 CAR 结构的设计成为 CAR-T 治疗的挑战。 中国
Clinical Advancement of EGFR Inhibitors in Cancer Therapy
The epidermal growth factor receptor (EGFR) represents one of the most promising molecular targets in cancer therapeutics. An array of EGFR inhibitory drugs have been developed that are progressing rapidly in oncology clinical trials
Phosphotyrosine Kinase Assays as a Prescreen for Inhibitors of EGFr
The epidermal growth factor receptor (EGFr) is a 170-kDa glycosylated transmembrane protein found in a wide variety of tissues (1 ). It is the receptor for epidermal growth factor (EGF), transforming growth factor α (TGFα), and other related
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