- ￥3000 - 3999
- Abbiotec
- 美国
- 250212
- 2025年07月12日
- E, IHC
- Mouse
- H
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant form of human activated protein C adsorbed on aluminum hydroxide gel
- 亚型：
Mouse IgG1
- 形态：
Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
- 保存条件：
Store at 4°C.
- 克隆性：
单克隆抗体
- 标记物：
见下方详细说明
- 适应物种：
H
- 宿主：
Mouse
- 应用范围：
E, IHC
- 浓度：
见详细说明信息
- 靶点：
Activated Protein C
- 抗体英文名：
Activated Protein C Antibody
- 抗体名：
Activated Protein C抗体
- 规格：
0.2 mg
Activated Protein C Antibody产品详细介绍：
| 产品名称： | Activated Protein C Antibody |
| 说明书： | http://www.abbiotec.com/antibodies/activated-protein-c-antibody【参考图片】 |
| 货号： | 250212 |
| 规格： | 0.2 mg |
| 产品描述： | Protein C is a vitamin K-dependent serine protease produced in the liver and made up of 2 polypeptide chains. The 62kDa proenzyme is activated by thrombin and the active enzyme cleaves factor Va and VIIIa and thus inhibits blood coagulation. The molecular weight of the active enzyme is 55kDa and the normal concentrations in human plasma is approximately 1-3 ng/ml because of the very fast turnover, the proenzyme concentration is approximately 3 µg/ml. The activated protein C (APC) is inhibited by members of the serine protease inhibitor (serpin) family, of which alpha1-antitrypsin (AAT) and protein C inhibitor (PCI) are the most important. This antibody is specific for a conformation-dependent neoepitope that is expressed in activated protein C upon complex-formation with alpha1-antitrypsin. No reaction is seen to non-complexed alpha1-antitrypsin and weak cross-reaction with protein C zymogen. The antibody specificity is calcium dependent. |
| 克隆类型： | Mouse Monoclonal Antibody |
| 亚型： | Mouse IgG1 |
| 免疫原： | Recombinant form of human activated protein C adsorbed on aluminum hydroxide gel |
| 适用物种： | H |
| 应用范围： | E, IHC |
| 应用说明： | Product Cat. No. 250212 reacts strongly with APC-AAT complexes in ELISA. It can be used in sandwich ELISA in combination with a polyclonal anti-protein C antiserum. Note, that the conformational neoepitope displayed in the APC-AAT complex can also be detected in APC coated directly onto a high-binding microtiter plate. E: 1:500; IHC: 1:100-1:500 |
| 别名： | Activated Protein C; Protein C; APC; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV |
| 形态： | Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography. |
| 保存条件： | Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
| 参考文献： |
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文献和实验Protein C (PC) is a 62-kDa vitamin K-dependent plasma zymogen which, after activation to serine protease, plays an important role in the physiologic regulation of blood coagulation. Given that PC is one of the major naturally
Combined 3C-ChIP-Cloning (6C) Assay: A Tool to Unravel Protein-Mediated Genome Architecture
between chromatin elements without specifically identifying the protein components that mediate such interactions. Here we describe a detailed protocol for C ombined 3C -C hIP-C loning (6C) technology, which combines multiple techniques to identify the proteins
ANTIBODY BINDING TO PROTEIN A AND PROTEIN G
., Finstad, J., Williams, Jr., R. C. 1970. Phylogenetic insight into evolution of mammalian Fc fragment of g G globulin using staphylococcal protein A. J. Immunol. 104:140-147. Kronvall, G. 1973. A surface component in group A, C, and G streptococci
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