Perlecan is an extracellular matrix proteoglycan. It has a large core protein of 400-450 kDa and is often produced with heparan sulfate side chains. Perlecan is found in basement membranes where it contributes to the permeability characteristics, serves as a substrate for vascular cells and binds growth factors involved in vascular remodelling. This antibody is highly specific for perlecan. There is no evidence for cross-reactivity with other connective tissue proteins (vitronectin, fibronectin, elastin, collagen, laminin This antibody reacts with human perlecan. Other species have not been tested.
克隆类型:
Mouse Monoclonal Antibody
亚型:
Mouse IgG1
免疫原:
Lysed bovine corneal endothelial cells and extracellular matrix
适用物种:
B, H
应用范围:
E, IHC, IP
应用说明:
Product Cat. No. 250260 can be used in immunoprecipitation, ELISA and immunostaining of frozen PLP-fixed sections of bovine and human tissues. Product Cat. No. 250260 is more sensitive than Product Cat. No. 250258 or Product Cat. No. 250259 in ELISA. E: 1:8,000; WB: 1:500; IHC: 1:100
别名:
HSPG; PLC; Basement memebrane-specific heparan sulfate proteoglacan core protein [precursor]
形态:
Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
保存条件:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.