- ￥3000 - 3999
- Abbiotec
- 美国
- 250206
- 2025年07月14日
- E
- Human Ig
- H
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 免疫原：
This is a non-immune hybridoma.
- 亚型：
Human IgE
- 形态：
Each vial contains 0.1 mg IgE in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-L affinity chromatography. 1 mg Human IgE corresponds to 380,000 ± 50,000 IU/ml. Biotinylation ratio: 2-4 biotin/IgE.
- 保存条件：
Store at -20°C. The material must be handled as potentially infectious as all human material.
- 克隆性：
见说明信息
- 标记物：
见下方详细说明
- 适应物种：
H
- 宿主：
Human Ig
- 应用范围：
E
- 浓度：
见详细说明信息
- 靶点：
Human IgE
- 抗体英文名：
Human IgE
- 抗体名：
Human IgE
- 规格：
0.1 mg
Human IgE产品详细介绍：
| 产品名称： | Human IgE |
| 说明书： | http://www.abbiotec.com/antibodies/Human-IgE-3【参考图片】 |
| 货号： | 250206 |
| 规格： | 0.1 mg |
| 产品描述： | This product is purified human IgE with kappa light chains produced in vitro from a hybridoma. Plasma IgE concentrations are low in normal patients. Elevated IgE levels are found in patients presenting severe allergic reactions and parasite infections. Original material was obtained from a healthy donor tested negative for HIV, HCV and hepatitis B by using US FDA-approved tests. Purity of human IgE is > 98% by SDS-PAGE analysis. There is no contamination by antibodies of other isotypes because of the cell line origin. Contaminants from foetal bovine serum were removed by Protein-L affinity chromatography. The material must be handled as potentially infectious as all human material. The product can be used as an IgE control in quantitative assays and for cell sensitization assays. |
| 克隆类型： | Human Ig, Biotin-conjugated Antibody, Control Antibody |
| 亚型： | Human IgE |
| 免疫原： | This is a non-immune hybridoma. |
| 适用物种： | H |
| 应用范围： | E |
| 应用说明： | Purified human IgE with kappa light chain is produced in vitro from a monoclonal hybridoma. Original material was obtained from a healthy donor tested negative for HIV, HCV and hepatitis B by using US FDA-approved tests. Purity of human IgE is >98% by SDS-PAGE analysis. Endotoxin level < 25 EU/mg. |
| 别名： | Immunoglobulin E; IgE |
| 形态： | Each vial contains 0.1 mg IgE in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-L affinity chromatography. 1 mg Human IgE corresponds to 380,000 ± 50,000 IU/ml. Biotinylation ratio: 2-4 biotin/IgE. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. The material must be handled as potentially infectious as all human material. Product is guaranteed one year from the date of shipment. |
| 参考文献： | [1] Janson C et al. 2012. PLoS ONE. 7(11):e49615. PMID# 23185384. [2] Ainsua-enrich e et al. 2012. Journal of Immunology. 189(6):2727-2734. PMID# 22896635. [3] Serra-Pages M et al. 2012 Journal of Leukocyte Biology. 92(6):1155-1165. PMID# 2285983. [4] Alvarez-Errico D et al. 2011. The Journal of Immunology. 187(11):5577-5586. PMID# 22068234. [5] Charles N et al. 2010. Nature Medicine. 16(701-707.PMID# 20512127. |
ABBIOTEC产品提供质量保证，提供完善的售后和技术支持，ABBIOTEC产品正品包装：
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
- 作者
- 内容
- 询问日期
文献和实验佚名 IgE是1966年发现的一类Ig，分子量为188kD，血清中含量极低，仅占血清总Ig的0.002%，在个体发育中合成较晚。ε链有4个CH（Cε1～Cε4），无铰链区，含有较多的半胱氨酸和甲硫氨酸。对热敏感，56℃、30分钟可使IgE丧失生物学活性。IgE主要由鼻咽部、扁桃体、支气管、胃肠等粘膜固有层的浆细胞产生，这些部位常是变应原入侵和I型变态
Detection of Class Switching and IgE Synthesis in Human B Cells
events leading to IgE synthesis. This chapter will illustrate how human B cells (na�ve or memory) can be purified, stored, and cultivated in medium that is permissive for IgE synthesis and stimulated with IL-4 or IL-13 and CD40 activation
IgE 与高亲和力IgE 受体 IgE主要由鼻咽、扁桃体、支气管、胃肠等处黏膜固有层中的浆细胞产生，这些部位也是变应原侵入并引起过敏反应的好发部位。IgE受体(FcεR)有两种类型：一类为高亲和力受体，即FcεR I(解离常数达1X10-10 M)，此类受体与Fc结合后的稳定性远高于其他Fc受体；另一类为低亲和力受体，称为FcεRⅡ，它和IgE结合的亲和力比FcεR1低100～1 000倍。研究发现FcεR I还有两个异构体，分别表达于IL-4刺激过的B细胞、单核细胞和嗜
技术资料暂无技术资料 索取技术资料
