Factor B is a component of the alternative pathway of complement activation. The protein consists of a single polypeptide chain of molecular mass 93 kDa, and has a concentration in plasma of approximately 200 ,mg/mL. Factor B is cleaved by factor D into the Ba component (30 kDa) and the Bb (63 kDa). Together with C3b, Bb forms the alternative pathway C3 convertase C3bBb. This antibody is specific for the Ba fragment of human factor B.
克隆类型:
Mouse Monoclonal Antibody
亚型:
Mouse IgG1/k
免疫原:
Complemen factor B purified from human plasma and adsorbed to aluminum hydroxide gel
适用物种:
H
应用范围:
E, WB
应用说明:
Product Cat. No. 250293 reacts strongly with human factor B. Strong reaction is seen when coated directly onto the microtiter well and also when used as detection antibody in sandwich ELISA with a polyclonal capture antibody against factor B. In Western blot, Product Cat. No. 250293 reacts with the Ba fragment of factor B in its non-reduced form only. E: 1:1,600; WB: 1:500