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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human claudin-5.
- 亚型:
Rabbit Ig
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
多克隆
- 标记物:
见下方详细说明
- 适应物种:
H, M, R
- 保质期:
1-2年
- 抗原来源:
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human claudin-5.
- 目录编号:
251609
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Rabbit
- 应用范围:
E, WB, IHC
- 浓度:
见详细说明信息
- 靶点:
Claudin-5
- 抗体英文名:
Claudin-5 Antibody
- 抗体名:
Claudin-5 Antibody
- 规格:
0.1 mg
Claudin-5 Antibody产品详细介绍:
| 产品名称: | Claudin-5 Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 251609 |
| 规格: | 0.1 mg |
| 产品描述: | Claudin-5 is a transmembrane protein that plays a major role in the “sealing” of tight junctions. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. |
| 克隆类型: | Rabbit Polyclonal Antibody |
| 亚型: | Rabbit Ig |
| 免疫原: | KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human claudin-5. |
| 适用物种: | H, M, R |
| 应用范围: | E, WB, IHC |
| 应用说明: | E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 别名: | Claudin-5; Transmembrane protein deleted in VCFS; TMDVCF; CLDN5; AWAL; TMVCF |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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文献和实验Tracing the Endocytosis of Claudin-5 in Brain Endothelial Cells
Claudin-5 is a transmembrane tight junction protein highly expressed in brain endothelial cells, the site of the blood–brain barrier. The properties of the brain endothelial tight junction complex are considered to be dependent on claudin-5
Claudin-5 Expression in In Vitro Models of the BloodBrain Barrier
of claudin-5 as expressed in three in vitro models of the BBB, and show that the contact co-culture of endothelial cells with glial cells significantly increases claudin-5 expression.
HIV-1-Induced Alterations of Claudin-5 Expression at the BloodBrain Barrier Level
a critical role in HIV-1-entry into the brain. Disruption of tight junctions, including changes in claudin-5 expression, is common in HIV-1-infected patients. Recent evidence indicates that both exposure to HIV-1 and HIV-1 specific proteins, such as Tat
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