- ￥3000 - 3999
- Abbiotec
- 美国
- 250974
- 2025年07月16日
- E, FC
- Mouse
- H
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
mouse IgM
- 形态：
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
- 保存条件：
Store at -20°C.
- 克隆性：
单克隆
- 标记物：
见下方详细说明
- 适应物种：
H
- 保质期：
1-2年
- 目录编号：
250974
- 级别：
超纯
- 库存：
大量
- 供应商：
Abbiotec
- 宿主：
Mouse
- 应用范围：
E, FC
- 浓度：
见详细说明信息
- 靶点：
CD57 (HI57a)
- 抗体英文名：
CD57 (HI57a) Antibody
- 抗体名：
CD57 (HI57a) Antibody
- 规格：
0.1 mg
CD57 (HI57a) Antibody产品详细介绍：
| 产品名称： | CD57 (HI57a) Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 250974 |
| 规格： | 0.1 mg |
| 产品描述： | The CD57 (HI57a) antibody recognizes a 110-115 kDa carbohydrate antigen also called B3GAT1, HNK-1 and Leu7. CD57 antigen is expressed on 12-20% of normal peripheral blood lymphocytes including subsets of NK cells and CD8+ Ts/Tc. CD57 expression increases with age in peripheral blood lymphocytes to 25-40% in patients over 80 year-old. CD57 is not expressed by cord blood lymphocytes, B lymphocytes, monocytes, granulocytes, platelets and erythrocytes. CD57+ cell population increases in pathologies characterized by an imbalance of CD4/CD8 lymphocytes, e.g. AIDS, autoimmune diseases, allograft transplants, and viral infections. The CD57 molecule is shared by normal neural and striated muscle and their neoplastic counterparts including neurofibromas, neurofibrosarcomas and malignant melanomas. CD57 is also present on normal and neoplastic prostatic epithelia, where it represents a prognostic factor showing a positive correlation between the number of CD57+ cells and an increased survival of the neoplastic patients. |
| 克隆类型： | Mouse Monoclonal Antibody |
| 亚型： | mouse IgM |
| 免疫原： | |
| 适用物种： | H |
| 应用范围： | E, FC |
| 应用说明： | E: 1:500-1:1,000; FC: 1:200-1:1,000 |
| 别名： | Beta-1,3-glucuronyltransferase 1; Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1; Glucuronosyltransferase-P; GlcAT-P; UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase; GlcUAT-P; B3GAT1; GLCATP; HNK-1; HSO(3)-3GlcAbeta1-3Galbeta1-4GlcNAc-; Leu7; CD57 |
| 形态： | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： | Tadamitsu K. et al., eds. 1997. Leucocyte Typing VI: White Cell Differentiation Antigens. P49-52, 113-114 Garland Publishing, Inc., New York. |
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文献和实验CD57 分子 CD57 常用单克隆抗体或代号： Leu7,HNK- 1 主要表达细胞： NKsub,Tsub [NK] 分子质量(kDa)和结构： gp110 功 能： 参与NK活化后的杀伤作用 CD57 Aka Leu7 Glycoprotein with cell adhesion functions NK cell marker and neuroendocrine marker
中。5. 用无菌 PBS 将上述锥形试管填满（至 50 mL)。介绍样品制备。6. 洗涤。在室温、低速制动条件下，以 300 X g 离心分离试管 10 分钟。7. 裂解红细胞（BD 产品目录号：555899，10 x 溶液。在蒸馏水中使用 1 x 溶液。室温孵育 15 分钟。）8. 将 1x106 PBMC 重悬于 20 μL 染色缓冲液中（PBS 含有 5% 正常人血清）。9. 加入抗体：CD117-BV421 (c-kit)、CD7-BV510、CD57- BV605、CD8-BV650
Identification of B-Cell Subsets: An Exposition of 11-Color (Hi-D) FACS Methods
. In this chapter, we describe 11-color high-dimensional (Hi-D) FACS staining and data analysis methods that provide greater clarity in identifying the B-cell subsets in bone marrow, spleen, and peritoneal cavity. Further, we show how a single Hi-D FACS antibody
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