CCR2 is the receptor for the MCP-1, MCP-3 and MCP-4 chemokines. CCR2 transduces a signal by increasing the intracellular calcium ion level. CCR2 is also the coreceptor with CD4 for HIV-1 infection. Variations in CCR2 are associated with relative resistance to immunodeficiency virus type 1.
克隆类型:
Rabbit Polyclonal Antibody
亚型:
Rabbit Ig
免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CCR-2.