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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human calpain-1.
- 亚型:
Rabbit Ig
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
多克隆
- 标记物:
见下方详细说明
- 适应物种:
H, M, R, P, B, Sh, Ck
- 保质期:
1-2年
- 抗原来源:
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human calpain-1.
- 目录编号:
251470
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Rabbit
- 应用范围:
E, WB, IHC, IP
- 浓度:
见详细说明信息
- 靶点:
Calpain-1
- 抗体英文名:
Calpain-1 Antibody
- 抗体名:
Calpain-1 Antibody
- 规格:
0.1 mg
Calpain-1 Antibody产品详细介绍:
| 产品名称: | Calpain-1 Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 251470 |
| 规格: | 0.1 mg |
| 产品描述: | Calpain-1 catalytic subunit (Calpain-1) is a calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Calpain-1 is activated by micromolar concentrations of calcium and inhibited by calpastatin. |
| 克隆类型: | Rabbit Polyclonal Antibody |
| 亚型: | Rabbit Ig |
| 免疫原: | KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human calpain-1. |
| 适用物种: | H, M, R, P, B, Sh, Ck |
| 应用范围: | E, WB, IHC, IP |
| 应用说明: | E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP: 1:100-1:500 |
| 别名: | Calpain-1; Calpain-1 catalytic subunit; Calpain-1 large subunit; Calcium-activated neutral proteinase 1; CANP 1; Calpain mu-type; muCANP; Micromolar-calpain; Cell proliferation-inducing gene 30 protein; CAPN1; CANPL1 |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: | Li Y et al. 2012. Biomedical and Life Sciences. Tumor Biology. 33(5):1403-1410. PMID# 22528939. |
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文献和实验themselves. The method presented here uses relatively simple and inexpensive equipment and reagents, although the assay of calpain activity is greatly simplified by access to a fluorometer with the ability to read microtiter plates.
developed for in vitro studies (4 ). Recently, we have refined this approach to apply to in vivo studies of acute CNS injury (5 ,6 ). This technique allows for differential and concurrent measurement of the two major isoforms of calpain, m-calpain and μ
Proteolysis of Cortactin by Calpain in Platelets and In Vitro
of rapid biochemical reactions, including tyrosine phosphorylation of various intracellular proteins and remodeling of the cytoskeleton. Calpain, a Ca2+ -dependent thiol protease, plays an important role in remodeling the platelet cytoskeleton
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