- ￥3000 - 3999
- Abbiotec
- 美国
- 200158
- 2025年07月15日
- E, WB
- Rabbit
- H, M, P
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ATM.
- 亚型：
Rabbit Ig
- 形态：
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
- 保存条件：
Store at -20°C.
- 克隆性：
多克隆抗体
- 标记物：
见下方详细说明
- 适应物种：
H, M, P
- 宿主：
Rabbit
- 应用范围：
E, WB
- 浓度：
见详细说明信息
- 靶点：
ATM
- 抗体英文名：
ATM Antibody
- 抗体名：
ATM抗体
- 规格：
0.1 mg
ATM Antibody产品详细介绍：
| 产品名称： | ATM Antibody |
| 说明书： | http://www.abbiotec.com/antibodies/atm-antibody【参考图片】 |
| 货号： | 200158 |
| 规格： | 0.1 mg |
| 产品描述： | Ataxia telangiectasia mutated (ATM) is a Ser/Thr protein kinase which activates checkpoint signaling upon double strand breaks, apoptosis and genotoxic stresses such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. ATM is also involved in signal transduction and cell cycle control and may function as a tumor suppressor. Defects in ATM are the cause of ataxia telangiectasia, leukemia, and lymphoma. |
| 克隆类型： | Rabbit Polyclonal Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ATM. |
| 适用物种： | H, M, P |
| 应用范围： | E, WB |
| 应用说明： | E: 1:500-1:1,000; WB: 1:100-1:500 |
| 别名： | Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated; ATM |
| 形态： | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
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文献和实验Analyzing the Regulation and Function of ATM
activity is measured using p531–44 -specific substrate or by immunoblotting extracts with an anti-phosphoserine 15 p53-specific antibody. Missense mutations affecting ATM kinase activity are detected using in vitro mutagenesis of ATM cDNA followed
hj841023 http://www.ncbi.nlm.nih.gov/nuccore/224514928?report=genbank&log$=seqview&from=11637691&to=11820525 刚开始着手实验前期工作，有很多不懂的，请教论坛里各位高手，如何看懂GenBank里的ATM基因DNA序列,以上是相关链接。谢谢各位指教了。:) freecell 请参考这个帖子： http
Expression and Assay of Recombinant ATM
A variety of genetic disorders involve genome instability and abnormal response to DNA damaging agents. Investigation of these disorders has revealed different metabolic pathways responsible for damage repair on one hand, and for signaling
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