万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Bovine brain S-100B
- 亚型:
Mouse IgG1
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.2% with 0.09% sodium azide. Antibody was purified by anti-mouse IgG affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
单克隆
- 标记物:
见下方详细说明
- 适应物种:
H, M, R, B
- 保质期:
1-2年
- 抗原来源:
Bovine brain S-100B
- 目录编号:
251795
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Mouse
- 应用范围:
E, WB, IHC
- 浓度:
见详细说明信息
- 靶点:
S-100
- 抗体英文名:
S-100 Antibody
- 抗体名:
S-100 Antibody
- 规格:
0.1 mg
S-100 Antibody产品详细介绍:
| 产品名称: | S-100 Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 251795 |
| 规格: | 0.1 mg |
| 产品描述: | S-100 protein is a 21-kDa component isolated first from the brain but later found in a wide variety of normal and neoplastic cells of mesodermal, neuroectodermal, and epithelial origins. The S-100 protein is found in 3 forms: S-100a(0), a homodimer of alpha-alpha subunits; S-100a, a heterodimer of alpha-beta subunits; and, S-100b, a homodimer of beta-beta subunits. S-100 binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction plays a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. S-100 weakly binds calcium but binds zinc with a higher affinity. Concentrations of potassium ions antagonize the binding of both divalent cations, especially calcium. |
| 克隆类型: | Mouse Monoclonal Antibody |
| 亚型: | Mouse IgG1 |
| 免疫原: | Bovine brain S-100B |
| 适用物种: | H, M, R, B |
| 应用范围: | E, WB, IHC |
| 应用说明: | E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 别名: | S-100 protein beta chain; S-100 protein subunit beta; S100 calcium-binding protein; S100B |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.2% with 0.09% sodium azide. Antibody was purified by anti-mouse IgG affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: | Aydogan A et al. 2012. Dept of Pathology. Faculty of Veterinary Medicine. Revue Med. Vet. 163(11):536-538 |
ABBIOTEC产品提供质量保证,提供完善的售后和技术支持,ABBIOTEC产品正品包装:
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Nature 综述导读:FDA 批准第 100 个抗体药物!抗体药物的研究方向在哪里?
批准了第 50 种抗体,距离第一个抗体已经过去了 29 年。2021 年 4 月,随着葛兰素史克 PD1 阻断剂 dostarlimab 的批准,抗体药物仅用了 6 年多的时间就达到了 100 个,进入了「百抗」新时代(图五)。 图五 Nature Reviews Drug Discovery 20, 10 (2021) 上面提到的 100 个抗体并不是单纯经典的单克隆的裸抗体(naked antibody),其中也包括了抗体片段已经工程化修饰抗体的各种偶联形式。其中包括有抗体药物偶联(ADC
Chimerization of a Monoclonal Antibody for Treating Hodgkin's Lymphoma
follicles and at the rim of germinal centers (2 ). Consequently, Ber-H2 has been utilized as an immunotoxin by conjugating the antibody to the ribosome-inactivating toxin Saporin to treat four patients with refractory Hodgkin’s lymphoma
人S 蛋白100B (S-100B) 酶联免疫分析 试剂盒使用说明书 本试剂仅供研究使用 目的:本试剂盒用于测定人血清,血浆及相关液体样本中S 蛋白100B (S-100B) 的含量。 实验原理: 本试剂盒应用双抗体夹心法测定标本中人 S 蛋白 100B (S-100B) 水平。用纯化的人 S 蛋白 100B (S-100B) 抗体包被微孔板,制成固相抗体,往包被单抗的微孔中依次加入 S 蛋白 100
技术资料暂无技术资料 索取技术资料









