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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human SPY.
- 亚型:
Rabbit Ig
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
多克隆
- 标记物:
见下方详细说明
- 适应物种:
H, M, R, B, Ck
- 保质期:
1-2年
- 抗原来源:
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human SPY.
- 目录编号:
251355
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Rabbit
- 应用范围:
E, WB, IHC, IP
- 浓度:
见详细说明信息
- 靶点:
SPY (spindly)
- 抗体英文名:
SPY (spindly) Antibody
- 抗体名:
SPY (spindly) Antibody
- 规格:
0.1 mg
SPY (spindly) Antibody产品详细介绍:
| 产品名称: | SPY (spindly) Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 251355 |
| 规格: | 0.1 mg |
| 产品描述: | O-linked N-acetylglucosamine transferase (SPY) catalyzes the addition of nucleotide-activated sugars directly onto the polypeptide through O-glycosidic linkage with the hydroxyl of serine or threonine.SPY is highly expressed in pancreas and to a lesser extent in skeletal muscle, heart, brain and placenta. SPY is present in trace amounts in lung and liver. |
| 克隆类型: | Rabbit Polyclonal Antibody |
| 亚型: | Rabbit Ig |
| 免疫原: | KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human SPY. |
| 适用物种: | H, M, R, B, Ck |
| 应用范围: | E, WB, IHC, IP |
| 应用说明: | E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP |
| 别名: | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit; O-GlcNAc transferase subunit p110; O-linked N-acetylglucosamine transferase 110 kDa subunit; OGT; SPY; Spindly |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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文献和实验Identification of O-linked -d-N-acetylglucosamine-Modified Proteins from Arabidopsis
processes, including transcription, signaling and cytokinesis and is associated with several diseases. Cycling of O-GlcNAc is tightly regulated by O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). Plants have two OGTs, SPINDLY (SPY) and SECRET AGENT (SEC
质上,而在 OGlcNAc 糖苷酶的催化作用下,糖基被从蛋白质上移除许多细胞活动过程,如蛋白转运入细胞核、转录、细胞骨架附着在细胞膜上或蛋白合成等都参与了这个糖基化修饰,目前对它的确切作用还了解不多。 植物中有关 OGlcNAc 糖基化的报道还很少,与 OGlcNAc 转移酶相似的两个被命名为 SPINDLY 和 SEC 的酶已在拟南芥中克隆出来 [ 11,13] 。它们在离体条件下具有 OGlcNAc 转移酶活性,但还不清楚它们在植物体内的天然底物。此外,有报道将一些细胞核蛋白描述为携带末端为 GlcNAc
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