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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within the center region ORF K2 from HHV-8 VIL-6.
- 亚型:
Rabbit Ig
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
多克隆
- 标记物:
见下方详细说明
- 适应物种:
Vs
- 保质期:
1-2年
- 抗原来源:
KLH-conjugated synthetic peptide encompassing a sequence within the center region ORF K2 from HHV-8 VIL-6.
- 目录编号:
251352
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Rabbit
- 应用范围:
E, WB, IHC
- 浓度:
见详细说明信息
- 靶点:
HHV-8 VIL-6
- 抗体英文名:
HHV-8 VIL-6 Antibody
- 抗体名:
HHV-8 VIL-6 Antibody
- 规格:
0.1 mg
HHV-8 VIL-6 Antibody产品详细介绍:
| 产品名称: | HHV-8 VIL-6 Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 251352 |
| 规格: | 0.1 mg |
| 产品描述: | Human herpesvirus 8 (HHV-8 or KSHV, Kaposi's sarcoma-associated herpesvirus) has been associated with classical, endemic (African), and AIDS-related Kaposi's sarcoma (KS), body cavity-based primary effusion lymphomas, and multicentric Castleman's disease (MCD). KSHV encodes more than 85 protein-coding genes. ORF K2 encodes a viral form of interleukin-6 (vIL-6), a cytokine that promotes the growth of KS and myeloma cells and is found at elevated levels in MCD lesions and patient sera. vIL-6 shares 25% amino-acid identity with human cellular IL-6. |
| 克隆类型: | Rabbit Polyclonal Antibody |
| 亚型: | Rabbit Ig |
| 免疫原: | KLH-conjugated synthetic peptide encompassing a sequence within the center region ORF K2 from HHV-8 VIL-6. |
| 适用物种: | Vs |
| 应用范围: | E, WB, IHC |
| 应用说明: | E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 别名: | HHV-8 VIL-6; HHV8 ORF K2; vIL-6; ORF K2; Human herpesvirus 8; Putative interleukin 6; Kaposi's sarcoma-associated herpesvirus VIL-6 |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: | [1] Wu J et al. 2014. PLoS ONE. 9(3):e93478. PMID#24675762. [2] Venkataraman G et al. 2013. American Journal of Clinical Pathology. 139: 651-661. PMID# 23596117 |
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文献和实验A sensitive quantification of HHV-6B by real-time PCR
Human herpesvirus (HHV)-6B is a pathogen causing latent infection in virtually all humans. Nevertheless, the interaction of HHV-6B with its host cells is poorly understood. Although HHV-6B is approximately 90% homologous to HHV-6A, it expresses
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,可通过对单克隆抗体反应性、特异性 pcr 、 dna 分析等试验来区别。又确证 cd4 分子是 hhv-7 的受体,抗 cd4 单克隆抗体可抑 hhv-7 在 cd4 t 细胞中增殖。由于 hhv-7 与 hiv 的受体皆为 cd4 分子,两者之间的互相拮抗作用,将为 hiv 的研究开辟了新的途径。
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