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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated MAP synthetic peptide corresponding to human angiotensinogen II.
- 亚型:
Rabbit Ig
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
多克隆
- 标记物:
见下方详细说明
- 适应物种:
H, M, R
- 保质期:
1-2年
- 抗原来源:
KLH-conjugated MAP synthetic peptide corresponding to human angiotensinogen II.
- 目录编号:
251229
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Rabbit
- 应用范围:
E, WB, IHC
- 浓度:
见详细说明信息
- 靶点:
Angiotensin II
- 抗体英文名:
Angiotensin II Antibody
- 抗体名:
Angiotensin II Antibody
- 规格:
0.1 mg
Angiotensin II Antibody产品详细介绍:
| 产品名称: | Angiotensin II Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 251229 |
| 规格: | 0.1 mg |
| 产品描述: | Angiotensin II is an essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. In response to lowered blood pressure, the enzyme renin cleaves angiotensinogen to produce angiotensin I (angiotensin 1-10). Angiotensin I is a substrate of ACE (angiotensin converting enzyme) that removes a dipeptide to yield the physiologically active peptide angiotensin II (angiotensin 1-8). Angiotensin II acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone. Genetic variations in angiotensin II are a cause of susceptibility to essential hypertension (EHT). Essential hypertension is a condition in which blood pressure is consistently higher than normal with no identifiable cause. |
| 克隆类型: | Rabbit Polyclonal Antibody |
| 亚型: | Rabbit Ig |
| 免疫原: | KLH-conjugated MAP synthetic peptide corresponding to human angiotensinogen II. |
| 适用物种: | H, M, R |
| 应用范围: | E, WB, IHC |
| 应用说明: | E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 别名: | Ang-II; Ang II; Angiotensin II; Angiotensin-2; AGT; Angiotensinogen; Serpin A8 |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: | Matsuura-Hachiya Y et al. 2013. Biochem. Biophys. Res. Commun. 442(1-2):34-43. PMID# 24216112 |
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文献和实验Characterization of Angiotensin II Receptors
Abstract Table of Contents Materials Figures Literature Cited Abstract Angiotensin II (Ang
Measurement of Renal Tubular Angiotensin II
, in part, by angiotensin II (Ang II), a peptide that is made up of eight amino acids. By activating Ang II receptors on both the basolateral and luminal membranes, Ang II serves a major function in determining how the kidney processes
Immunohistochemical Detection of Angiotensin II Receptor
for cell-specific localization of receptor expression within tissue. The resolution and sensitivity achieved with IHC is far greater than that obtained with classic autoradiography techniques although antireceptor antibody
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