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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within the N-term of human GABA-B-R1.
- 亚型:
Rabbit Ig
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
多克隆
- 标记物:
见下方详细说明
- 适应物种:
H, M, R, D, B, Hs
- 保质期:
1-2年
- 抗原来源:
KLH-conjugated synthetic peptide encompassing a sequence within the N-term of human GABA-B-R1.
- 目录编号:
251185
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Rabbit
- 应用范围:
E, WB, IHC, IP
- 浓度:
见详细说明信息
- 靶点:
GABA-B-R1
- 抗体英文名:
GABA-B-R1 Antibody
- 抗体名:
GABA-B-R1 Antibody
- 规格:
0.1 mg
GABA-B-R1 Antibody产品详细介绍:
| 产品名称: | GABA-B-R1 Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 251185 |
| 规格: | 0.1 mg |
| 产品描述: | GABA-B-R1 is a receptor for GABA. The activity of GABA-B-R1 is mediated by G-proteins that inhibit adenylyl cyclase activity, stimulate phospholipase A2, activate potassium channels, inactivate voltage-dependent calcium-channels and modulates inositol phospholipids hydrolysis. GABA-B-R1 plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA-B-R inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA-B-R decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. GABA-B-R1 is not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception. |
| 克隆类型: | Rabbit Polyclonal Antibody |
| 亚型: | Rabbit Ig |
| 免疫原: | KLH-conjugated synthetic peptide encompassing a sequence within the N-term of human GABA-B-R1. |
| 适用物种: | H, M, R, D, B, Hs |
| 应用范围: | E, WB, IHC, IP |
| 应用说明: | E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP: 1:100-1:500 |
| 别名: | Gamma-aminobutyric acid type B receptor subunit 1; GABA-B receptor 1; GABA-B-R1; Gb1; GABBR1 |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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文献和实验Characterization of GABA Receptors
'Hara, B.F., Kasch, L.M., Montrose‐Rafizadeh, C., Donovan, D.M., Shimada, S., Antonarakis, S.E., Guggino, W.B., Uhl, G.R., and Kazazian, H.H. 1991. Cloning of the γ‐aminobutyric acid (GABA) ρ 1 cDNA: A GABA receptor subunit highly expressed in the retina
大鼠γ氨基丁酸 (GABA) 酶联免疫分析( ELISA ) 试剂盒使用说明书 本试剂仅供研究使用 目的:本试剂盒用于测定大鼠血清,血浆, 组织及相关液体样本中 γ氨基丁酸(GABA) 含量。 实验原理: 本试剂盒应用双抗体夹心法测定标本中 大鼠γ氨基丁酸 (GABA) 水平。用纯化的 大鼠γ氨基丁酸 (GABA) 抗体包被微孔板,制成固相抗体,往包被单抗的微孔中依次加入 γ氨
A Homogeneous Assay to Assess GABA Transporter Activity
. Borden, L.A., Dhar, T.G.M., Smith, K.E., Weinshank, R.L., Branchek, T.A., and Gluchowski, C. 1994. Tiagabine, SK&F 89976‐A, CI‐966, and NNC‐711 are selective for the cloned GABA transporter GAT‐1. Eur. J
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