北京重组人Serpin A12(丝氨酸蛋白酶抑制剂A12)价

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博主要从事生物试剂的生产和销*(代"售")，产品线涵盖北京重组人Serpin A12(丝*酸蛋白酶抑制剂A12)价格厂家在内的分子生物学试剂产品，还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。

名称：北京重组人Serpin A12(丝*酸蛋白酶抑制剂A12)价格厂家
英文名：Recombinant Human Serine Protease Inhibitor-clade A12
品牌：百奥莱博
产地：国产|进口
规格：10μg|50μg|500μg|1mg
编号：JN1669
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Leu21-Lys414在N端带有GST标签。

Serpin A12质量控制：＞95%(还原性SDS-PAGE)

Serpin A12制剂：液体

Serpin A12保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于Serpin A12：
Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three β-sheets, nine α-helices, and one central loop; the structure is part of the set of distinctive features that are descriptive of Serpin family members. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat. and could be associated with parameters of obesity, insulin resistance, and glucose metabolism. These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the obesity metabolic syndrome.

欲咨询购买北京重组人Serpin A12(丝*酸蛋白酶抑制剂A12)价格厂家，请致电北京百奥莱博科技有限公司，为您提供最全面周到的产品服务，除此之外，我公司正在促销以下产品：

·重组人PIK3IP1(磷脂酰肌醇-3激酶相互作用蛋白1)
编号：JN1144
英文名称：Recombinant Human Phosphoinositide-3-kinase-interacting protein 1
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ser22-Thr168在C端含有His标签。

PIK3IP1质量控制：＞95%(还原性SDS-PAGE)

PIK3IP1制剂：冻干品

PIK3IP1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

PIK3IP1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于PIK3IP1：
Phosphoinositide-3-kinase-interacting protein 1(PIK3IP1) is an enzyme that in humans is encoded by the PIK3IP1 gene.It is a negative regulator of phosphatidylinositol-3-kinase (PI3K), suppresses the development of hepatocellular carcinoma. The gene encoding PIK3IP1 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.


北京重组人Serpin A12(丝*酸蛋白酶抑制剂A12)价格厂家关键词：重组Serpin A12,重组人丝*酸蛋白酶抑制剂A12,JN1669,重组人Serpin A12蛋白


·重组人LAIR1(白细胞相关免疫球蛋白样受体1)
编号：JN1678
英文名称：Recombinant Human Leukocyte-Associated Immunoglobulin-Like Receptor 1
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gln22-His163在C端含有His标签。

LAIR1质量控制：＞95%(还原性SDS-PAGE)

LAIR1制剂：冻干品

LAIR1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

LAIR1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于LAIR1：
Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) is a single-pass type I membrane protein. LAIR1 expressed on the majority of peripheral mononuclear cells, including natural killer (NK) cells, T-cells, B-cells, monocytes, and dendritic cells, highly in naive T-cells and B-cells. As an inhibitory receptor, LAIR1 plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation. LAIR1 plays inhibitory role independently of SH2-containing phosphatases and modulates cytokine production in CD4+ T-cells. It down-regulates IL2 and IFNG production while inducing secretion of transforming growth factor beta, also down-regulates IgG and IgE production in B-cells as well as IL8, IL10 and TNF secretion. LAIR1 inhibits the differentiation of peripheral blood precursors towards dendritic cells. It also restrains proliferation and induces apoptosis in myeloid leukemia cell lines as well as prevents nuclear translocation of NF-kappa-B p65 subunit/RELA and phosphorylation of I-kappa-B alpha/CHUK in these cells.


北京重组人Serpin A12(丝*酸蛋白酶抑制剂A12)价格厂家关键词：重组Serpin A12,重组人丝*酸蛋白酶抑制剂A12,JN1669,重组人Serpin A12蛋白

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