重组人TNFα(TNFSF2)现货价格

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专注于生命科学和生物技术领域，致力于为客户提供包括重组人TNFα(TNFSF2)现货价格在内的一系列分子生物学试剂产品，并提供一系列相关的技术服务。

名称：重组人TNFα(TNFSF2)现货价格
规格：10μg|50μg|500μg|1mg
编号：JN0438
产地：国产|进口
英文名：Recombinant Human Tumor Necrosis Factor alpha
品牌：百奥莱博
本品由我们的大肠杆菌表达系统制备而成。

TNFa/TNFSF2 (high active)质量控制：＞95%(还原性SDS-PAGE)


TNFa/TNFSF2 (high active)制剂：冻干品

TNFa/TNFSF2 (high active)保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

TNFa/TNFSF2 (high active)复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于TNFa/TNFSF2 (high active)：
Tumor Necrosis Factor-α (TNF-α) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressing CD4 secrete TNF-α while cells that express CD8 secrete little or no TNF-α. Synthesis of TNF-α can be induced by many different stimuli including interferons, IL2, and GM-CSF. The clinical use of the potent anti-tumor activity of TNF-α has been limited by the proinflammatory side effects such as fever, dose-limiting hypotension, hepatotoxicity, intravascular thrombosis, and hemorrhage. Designing clinically applicable TNF-α mutants with low systemic toxicity has been of intense pharmacological interest. Human TNF-α that binds to murine TNF-R55 but not murine TNF-R7, exhibits retained anti-tumor activity and reduced systemic toxicity in mice comp*(代"a")red with murine TNF-α, which binds to both murine TNF receptors. Based on these results, many TNF-α mutants that selectively bind to TNF-R55 have been designed. These mutants displayed cytotoxic activities on tumor cell lines in vitro and have exhibited lower systemic toxicity in vivo. Recombinant Human TNF-α High Active Mutant differs from the wild-type by amino acid subsitution of amino acids 1-7 with Arg8, Lys9, Arg10 and Phe157. This mutant form has been shown to have increased activity with less inflammatory side effects in vivo.


我公司的重组人TNFα(TNFSF2)现货价格，性价比高，货期短，送货上门，欢迎您来电咨询购买，另外，我公司还生产供应销*(代"售")下列产品：
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重组人TNFα(TNFSF2)现货价格关键词：重组人TNFα蛋白,重组TNFα,重组人TNFSF2,JN0438

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重组人TNFα(TNFSF2)现货价格关键词：重组人TNFα蛋白,重组TNFα,重组人TNFSF2,JN0438


·重组人β-防御素4A
编号：JN1925
英文名称：Recombinant Human beta-Defensin 4A
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Gly24-Pro64表达纯化得来。

β-Defensin4A质量控制：＞95%(还原性SDS-PAGE)

β-Defensin4A制剂：冻干品

β-Defensin4A保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

β-Defensin4A复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于β-Defensin4A：
β-Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 β-Defensins, which are distinguished from α-Defensins by the connectivity pattern of their three intermolecular disulfide bonds. Members of the Defensin family are highly similar in protein sequence. This gene encodes Defensin, DEFB4;, which has broad-spectrum antimicrobial activity and may play an important role in innate epithelial defense. They are highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. β-Defensin 4A has low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. The 45 amino acid mature human BD3 shares 38% and 33% amino acid sequence identity with mouse and rat BD3, respectively.

北京百莱博科技有限公司是分子生物学试剂产品的专业生产供应销*(代"售")商，恭候您的咨询选购重组人TNFα(TNFSF2)现货价格。