Recombinant Mouse Flt3L/Fms-re

Recombinant Mouse Flt3L/Fms-related tyrosine kinase 3 ligand  (CC19)

 

产品说明(Description)

Recombinant Mouse Fms-like Tyrosine Kinase 3 Ligand is produced by our Mammalian expression system and the target gene encoding Gly27-Arg188 is expressed with a 6His tag at the C-terminus. 

Accession #: P49772

Known as: Fms-related tyrosine kinase 3 ligand (Flt3L);  SL cytokine; Flt3 ligand; 

 

制剂(Formulation)

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4  .

 

质量控制(Quality Control)

Purity:           Greater than 95% as determined by reducing SDS-PAGE.    

Endotoxin:    Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

 

复溶(Reconstitution)

Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.    

 

保存(Storage)

Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.     

 

背景(Background)

Fms-related tyrosine kinase 3 ligand(Flt3L) is a single-pass type I membrane protein and consists of 232 amino acids. Flt3L is a hematopoietic four helical bundle cytokine, structurally homologous to stem cell factor and colony stimulating factor. Flt3L synergizes well with a number of other colony stimulating factors and interleukins. Flt3L stimulates the proliferation and differentiation of various blood cell progentiors by activating FLT3.

 

电泳(SDS-PAGE)

 

参考文献(References)

Intra-heterogeneity in transcription and chemoresistant property of leukemia-initiating cells in murine Setd2−/− acute myeloid leukemia[J]. Jiachun Song. et al. Cancer Communications. 2021.

 

FOR RESEARCH USE ONLY