- ￥840 - 2520
- 近岸蛋白(Novoprotein)
- CH53
- 中国
- 2026年05月06日
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- 详细信息
- 文献和实验
- 技术资料
- 英文名：
Recombinant Human FGFa (154AA)
- 规格：
10ug/50ug/500ug/1mg
| 规格： | 10ug | 产品价格： | ￥840.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥2520.0 |
| 规格： | 500ug | 产品价格： | 询价 |
| 规格： | 1mg | 产品价格： | 询价 |
Recombinant Human FGFa (154AA) (CH53)
产品说明(Description)
Recombinant Human Fibroblast growth factor 1/Fibroblast Growth Factor Acidic is produced by our E.coli expression system and the target gene encoding Ala2-Asp155 is expressed.
Accession #: P05230
Known as: Fibroblast Growth Factor 1; FGF-1; Acidic Fibroblast Growth Factor; aFGF; Endothelial Cell Growth Factor; ECGFHeparin-Binding Growth Factor 1; HBGF-1; FGF1; FGFA
制剂（Formulation）
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
质量控制（Quality Control）
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin: Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
复溶（Reconstitution）
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
保存（Storage）
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
背景（Background）
FGF acidic, also known as ECGF, FGF-1and HBGF-1, is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. It is a mitogenic peptide that is produced by multiple cell types and stimulates the proliferation of cells of mesodermal, ectodermal, and endodermal origin. Its association with heparan sulfate is a prerequisite for activation of FGF receptors. Internalized FGF acidic migrates to the nucleus where it is phosphorylated by nuclear PKC delta, exported to the cytosol, dephosphorylated, and degraded. Intracellular FGF acidic inhibits p53 activity and proapoptotic signaling.
电泳(SDS-PAGE)
参考文献(Reference)
Fibroblast Growth Factor-1 Improves Insulin Resistance via Repression of JNK-Mediated Inflammation[J]. Lei Fan. et al. frontiers in Pharmacology. 2019.
FOR RESEARCH USE ONLY
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