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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20°C 干燥
- 保质期:
12个月
- 英文名:
Ryanodine
- 供应商:
上海汇谱仪器有限公司
- CAS号:
15662-33-6
- 规格:
1 mg
概述
- 产品名称
Ryanodine - 描述
Ca2+ release modulator - 生物学描述
Alkaloid that binds with high affinity to ryanodine receptors to modulate intracellular Ca2+ release. Has complex actions and may stimulate or inhibit Ca2+ release, depending on the concentration used. - 纯度
> 98%
性能
- 化学名称
1H-Pyrrole-2-carboxylic acid (3S,4R,4aR,6S,7S,8R,8aS,8bR,9S,9aS)-dodecahydro-4,6,7,8a,8b,9a-hexahydroxy-3,6a,9-trimethyl-7-(1-methylethyl)-6,9-methanobenzo[1,2] pentaleno[1,6-bc]furan-8-yl ester - 分子量
493.55 - 化学结构

- 分子式
C25H35NO9 - CAS编号
15662-33-6 - 存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. - 溶解度概述
Soluble in ethanol to 10 mM - 处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- SMILES
CC(C)[C@@]6(O)C(OC(=O)c1cccn1)[C@]2(O)[C@@]5(O)[C@@]34O[C@@](O)(C[C@@]2(C)[C@@]4(O)CC[C@H](C)[C@H]3O)[C@]56C - 来源
Ryania speciosa
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文献和实验Detection of Calcium Release via Ryanodine Receptors
The ryanodine receptor ion channels (RyRs) release Ca2+ from the endo/sarcoplasmic reticulum in a variety of nonvertebrate and vertebrate species including flies, crustaceans, birds, fish, and amphibians. They are most abundant in skeletal
has been identified as a high-affinity receptor for the plant alkaloid ryanodine, and purified to apparent homogeneity as a 30s protein complex comprising four identical high- mol-wt polypeptide subunits of relative mol mass (M r ) ~560,000 (it1
Measurement of Calcium Release Due to Inositol Trisphosphate Receptors in Skeletal Muscle
from ryanodine receptors associated to excitation-contraction coupling. The study of slow calcium transients, however, is relevant due to their function in regulation of muscle gene expression and in the process of excitation-transcription coupling. Discussed
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