GR 125743

概述

• 产品名称
  GR 125743
• 描述
  5-HT_1B/1D antagonist
• 生物学描述
  5-HT_{1B / 1D} antagonist (pK_i = 8.5), often used in tritiated form as a radiolabelled probe. Shows approx. 100-fold selectivity over other 5-HT receptors and shows CNS and oral activity.
• 纯度
  > 99%

性能

• 化学名称
  N-[4-Methoxy-3-(4-methylpiperazin-1-yl)phenyl]-3-methyl-4-(pyridin-4-yl)benzamide
• 分子量
  416.52
• 化学结构
  
• 分子式
  C₂₅H₂₈N₄O₂
• CAS编号
  148547-33-5
• PubChem识别号
  5311130
• 存放说明
  Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
• 溶解度概述
  Soluble in ethanol to 25 mM
• 处理

  Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

• SMILES
  CN1CCN(CC1)c4cc(NC(=O)c3ccc(c2ccncc2)c(C)c3)ccc4OC
• 来源

  Synthetic