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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
室温存放
- 保质期:
12个月
- 英文名:
Nimodipine
- 供应商:
上海汇谱仪器有限公司
- CAS号:
66085-59-4
- 规格:
100 mg
概述
- 产品名称
Nimodipine - 描述
L-type Ca2+ channel blocker - 生物学描述
L-type Ca2+ channel blocker. Potent cerebrovasodilator. Cognitive enhancer. More lipophilic than nifedipine (ab120135). - 纯度
> 98% - 常规说明
Nimodipine is light sensitive and it is recommended that the compound is protected from light.
性能
- 化学名称
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methoxyethyl 1-methylethyl ester - 分子量
418.44 - 化学结构

- 分子式
C21H26N2O7 - CAS编号
66085-59-4 - PubChem识别号
4497 - 存放说明
Store at Room Temperature. The product can be stored for up to 12 months. - 溶解度概述
Soluble in DMSO to 100 mM and in ethanol to 10 mM - 处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- SMILES
CC=1NC(C)=C(C(C=1C(=O)OC(C)C)c2cccc(c2)[N+]([O-])=O)C(=O)OCCOC - 来源
Synthetic
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文献和实验硝苯地平在化学结构上属二氢吡啶类,这类钙拮抗药发展较快,在作用和药代动力学方面都有所改进,主要有以下几种: 尼卡地平(nicardipine)舒张血管较硝苯地平强,对脑血管有一定选择作用。尼索地平(nisoldipine)舒张血管作用更强,对冠状血管选择性较强,治疗心绞痛及 高血压 良效。尼莫地平(nimodipine)对脑血管有选择作用而降压作用较弱,用于治疗脑血管痉挛收缩及脑供血不足等疾病,也可防治偏头痛。尼群地平
良效。尼莫地平(nimodipine)对脑血管有选择作用而降压作用较弱,用于治疗脑血管痉挛收缩及脑供血不足等疾病,也可防治偏头痛。尼群地平(nitrendipine)血管舒张作用强大,用于治疗 高血压 。非洛地平(felodipine)对冠状血管及外周血管作用明显,持效较久,用于治疗心绞痛及 高血压 。伊拉地平(isradipine)对冠脉、脑及外周血管作用较强较久,用于治疗高血压及稳定型心绞痛。氨氯地平(amlodipine)舒张冠脉及外周血管,用于
nicotinic acid methyldopa nifedipine retard methyldopahydrazine nifedipine , methylnorethindrone nikethamide methylphenidate nimodipine
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