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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
冷藏
- 保质期:
长期
- 英文名:
Recombinant Human Matrix Metalloproteinase-3
- 库存:
335
- 供应商:
北京百奥莱博科技有限公司
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专注于生命科学和生物技术领域,致力于为客户提供包括北京现货重组人MMP-3(基质金属蛋白酶3)厂家在内的一系列分子生物学试剂产品,并提供一系列相关的技术服务。
名称:北京现货重组人MMP-3(基质金属蛋白酶3)厂家
编号:JN1682
英文名:Recombinant Human Matrix Metalloproteinase-3
品牌:百奥莱博
规格:10μg|50μg|500μg|1mg
产地:国产|进口
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Tyr18-Cys477在C端含有His标签。
MMP-3质量控制:>95%(还原性SDS-PAGE)
MMP-3制剂:液体
MMP-3保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于MMP-3:
MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling.[3] The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.
想要了解更多关于北京现货重组人MMP-3(基质金属蛋白酶3)厂家的价格、品牌、厂家、说明书、促销信息,请和我们联系。此外我公司还销*(代"售")下面的产品:
·重组小鼠SHH蛋白
编号:JN1212
英文名称:Recombinant Mouse Sonic Hedgehog
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Cys25-Gly198表达纯化得来。
SHH质量控制:>95%(还原性SDS-PAGE)
SHH制剂:冻干品
SHH保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
SHH复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于SHH:
Mouse Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic development. SHH is expressed in various embryonic tissues and plays critical roles in regulating the patterning of many systems, such as limbs and brain. SHH also plays an important role in adult, including the division of adult stem cells and the development of certain cancers and other diseases.Mouse Shh is synthesized as a 437 aa precursor that contains a 24 aa signal sequence and a 413 aa mature region. The mature region is autocatalytically processed into a nonglycosylated, 20 kDa, 174 aa Nterminal fragment (ShhN), and a catalyticprocessing,glycosylated, 34 kDa, 239 aa Cterminal fragment. The 20 kDa ShhN fragment is the core of the active hedgehog molecule. Mouse ShhN is 99%, 98%, and 100% aa identical to human, rat and gerbil ShhN, respectively.
北京现货重组人MMP-3(基质金属蛋白酶3)厂家关键词:重组人MMP-3,重组人基质金属蛋白酶3,重组MMP-3,重组人MMP-3蛋白,JN1682
·重组小鼠组织蛋白酶S(Cathepsin-S)(CTSS)
编号:JN1489
英文名称:Recombinant Mouse Cathepsin S
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Val18-Ile340在C端含有His标签。
Cathepsin-S/CTSS 质量控制:>95%(还原性SDS-PAGE)
Cathepsin-S/CTSS 制剂:冻干品
Cathepsin-S/CTSS 保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
Cathepsin-S/CTSS 复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于Cathepsin-S/CTSS :
Cathepsin S is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia. Moreover, cathepsin S is expressed in some epithelial cells. Comp*(代"a")red with the abundant cathepsins B, L and H, cathepsin S shows a restricted tissue distribution, with highest levels in spleen, heart, and lung. In addition, evidences indicated that cathepsin S generates A beta from amyloidogenic fragments of beta APP in the endosomal/lysosomal comp*(代"a")rtment, and is implicated in the pathogenesis of Alzheimer’s disease (AD) and Down Syndrome (DS).
北京现货重组人MMP-3(基质金属蛋白酶3)厂家关键词:重组人MMP-3,重组人基质金属蛋白酶3,重组MMP-3,重组人MMP-3蛋白,JN1682
·重组人ACOT13(酰基辅酶A硫酯酶13)
编号:JN0754
英文名称:Recombinant Human Acyl-Coenzyme A Thioesterase 13
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Thr2-Asn140在C端含有His标签。
ACOT13质量控制:>95%(还原性SDS-PAGE)
ACOT13制剂:冻干品
ACOT13保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
ACOT13复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于ACOT13:
Acyl-coenzyme A thioesterase 13, also known as Thioesterase superfamily member 2, ACOT13, THEM2 and PNAS-27, is a member of the thioesterase PaaI family. Acyl-CoA thioesterases catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. THEM2 is a cytoplasmic protein and exsis in a homotetramer. THEM2 has been identified as an interacting protein of phosphatidylcholine transfer protein. THEM2 also regulates hepatic lipid and glucose metabolism.
我公司正在优惠促销分子生物学试剂等系列产品,期待您的咨询选购北京现货重组人MMP-3(基质金属蛋白酶3)厂家。
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文献和实验活性的话,也可能出现高度降解的情况。如重组人基质金属蛋白酶3(MMP-3)被认为有促使哺乳动物上皮细胞凋亡的作用。它在Pp中高度降解,仅当与其组织抑制物TIMP-1共表达时才能保持稳定。这也提醒我们外源基因本身对产物稳定性的影响同样重要。 7、翻译后修饰 一般情况下Pp能产生较酿酒酵母明显要短的高甘露糖型寡糖链,且较均一,长度在8-14个之间,使产物更加稳定,而这正是Pp表达外源蛋白的一个优势。虽然糖基化对某些外源蛋白的活性没有太大影响,它却可能在蛋白折叠和抗蛋白酶降解中起重要作用。然而,糖
),也可认为是一种有通透性的支架( permeable supports )。更准确地说, Transwell 应该是一种实验技术,这项技术的主要材料是 Transwell 小室( Transwell chamber , Transwell insert ),其外形为一个可放置在孔板里的小杯子,不同厂家对 Transwell 会有不同的命名,而不同型号也可有不同形状,不同大小,根据实验需要,可有不同选择。但无论是何种外形,其关键部分都是一致的,那就是杯子底层的一张有通透性的膜 ,而杯子其余部分
如SMD1163、SMD1165或SMD1168亦可避免产物降解的发生。虽然并不是每一种外源蛋白都会受内源性蛋白酶的影响,但在未知其有无降解可能的情况下可以考虑使用此种宿主菌。 在另外一种情况下,如果基因工程产物会影响宿主菌生长代谢活性的话,也可能出现高度降解的情况。如重组人基质金属蛋白酶3(MMP-3)被认为有促使哺乳动物上皮细胞凋亡的作用。它在Pp中高度降解,仅当与其组织抑制物TIMP-1共表达时才能保持稳定。这也提醒我们外源基因本身对产物稳定性的影响同样重要。 8、翻译后修饰 一般情况
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