JN1564型重组人IL-1R1(IL-1 RI)(C端带F

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专业生产供应JN1564型重组人IL-1R1(IL-1 RI)(C端带Fc标签)价格，我公司销*(代"售")全品类的分子生物学试剂，价格优惠，欢迎广大科研工作者垂询订购。

名称：JN1564型重组人IL-1R1(IL-1 RI)(C端带Fc标签)价格
英文名：Recombinant Human Interleukin-1 receptor type 1/IL-1R-1
产地：国产|进口
编号：JN1564
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Leu18-Thr332在C端带有Fc标签。

IL-1R1/IL-1 RI质量控制：＞95%(还原性SDS-PAGE)

IL-1R1/IL-1 RI制剂：冻干品

IL-1R1/IL-1 RI保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

IL-1R1/IL-1 RI复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于IL-1R1/IL-1 RI：
Interleukin 1 receptor, type I (IL-1R1) is an interleukin receptor that belongs to the interleukin-1 receptor family. IL-1R1 is an 80 kDa transmembrane protein that is expressed predominantly by T cells, fibroblasts, and endothelial cells. This gene along with IL1R2, IL1RL2, and IL1RL1 form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. IL-1R1 is an important mediator involved in many cytokine induced immune and inflammatory responses. It binds to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. The signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. It also binds ligands with comp*(代"a")rable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. An IL1 receptor accessory protein that can heterodimerize with the Type I receptor in the presence of IL1α or IL1β but not IL1ra, was identified. Recombinant IL1 soluble receptor Type I is a potent antagonist of IL1 action.

欲咨询购买JN1564型重组人IL-1R1(IL-1 RI)(C端带Fc标签)价格，请致电北京百奥莱博科技有限公司，为您提供最全面周到的产品服务，除此之外，我公司正在促销以下产品：
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JN1564型重组人IL-1R1(IL-1 RI)(C端带Fc标签)价格关键词：重组人IL-1 RI,重组人IL-1R1蛋白,C端带Fc标签,JN1564


·重组人PDCD1(PD-1)(CD279)
编号：JN1526
英文名称：Recombinant Human Programmed Cell Death Protein 1
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Leu25-Gln167在C端带有Fc标签。

PDCD1/PD-1/CD279质量控制：＞95%(还原性SDS-PAGE)

PDCD1/PD-1/CD279制剂：冻干品

PDCD1/PD-1/CD279保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

PDCD1/PD-1/CD279复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于PDCD1/PD-1/CD279：
Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PDCD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. PDCD1 has been suggested to be involved in lymphocyte clonal selection and peripheral tolerance, and thus contributes to the prevention of autoimmune diseases. As a cell surface molecule, PDCD1 regulates the adaptive immune response. Engagement of PD-1 by its ligands PD-L1 or PD-L2 transduces a signal that inhibits T-cell proliferation, cytokine production, and cytolytic function.


JN1564型重组人IL-1R1(IL-1 RI)(C端带Fc标签)价格关键词：重组人IL-1 RI,重组人IL-1R1蛋白,C端带Fc标签,JN1564

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