JN1550型重组小鼠溶酶体整合膜蛋白(LIMPII)(SR

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博主要从事生物试剂的生产和销*(代"售")，产品线涵盖JN1550型重组小鼠溶酶体整合膜蛋白(LIMPII)(SR-B2)打折促销在内的分子生物学试剂产品，还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。

名称：JN1550型重组小鼠溶酶体整合膜蛋白(LIMPII)(SR-B2)打折促销
英文名：Recombinant Mouse Lysosomal Integral Membrane Protein II
规格：10μg|50μg|500μg|1mg
品牌：百奥莱博
产地：国产|进口
编号：JN1550
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Arg27-Thr432在C端含有His标签。

LIMPII/SR-B2 质量控制：＞95%(还原性SDS-PAGE)

LIMPII/SR-B2 制剂：冻干品

LIMPII/SR-B2 保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

LIMPII/SR-B2 复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于LIMPII/SR-B2 ：
Lysosome membrane protein II (LIMPII)，also known as SCARB2, is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal comp*(代"a")rtment. The protein deficiency in mice was reported to imp*(代"a")ir cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is identified as a receptor for EV71 (human enterovirus species A, Enterovirus 71) and CVA16 (coxsackievirus A16) which are most frequently associated with hand, foot and mouth disease (HFMD). Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. In addition, LIMPII also has been shown to bind thrombospondin-1, may contribute to the pro-adhesive changes of activated platelets during coagulation, and inflammation.

关于JN1550型重组小鼠溶酶体整合膜蛋白(LIMPII)(SR-B2)打折促销的更详细说明，请致电我公司咨询，我们将以最饱满的热情为您提供解答，此外，我公司专业供应下列产品：

·重组人TNFSF10(TRAIL)
编号：JN0437
英文名称：Recombinant Human TNF-Related Apoptosis-Inducing Ligand
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Arg115-Gly281表达纯化得来。

TNFSF10/TRAIL质量控制：＞95%(还原性SDS-PAGE)


TNFSF10/TRAIL制剂：冻干品

TNFSF10/TRAIL保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

TNFSF10/TRAIL复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于TNFSF10/TRAIL：
Human TNFSF10 is a type II transmembrane protein with an intracellular N-terminus and a ‘TNF homology domain’ (THD) at the extracellular C terminus. TNFSF10 can interact with several distinct receptors. Two of these receptors that belongs to TNFR superfamily, DR4 (TRAIL-R1) and DR5 (TRAIL-R2/TRICK2), are plasma membrane proteins containing intracellular death domains essential for activating apoptosis. TNFSF10 is promising for cancer therapy because it is cytotoxic and activates apoptosis in the majority of malignant cells, but not in normal cells.


JN1550型重组小鼠溶酶体整合膜蛋白(LIMPII)(SR-B2)打折促销关键词：JN1550,重组小鼠SR-B2,重组小鼠溶酶体整合膜蛋白,重组小鼠溶酶体整合膜蛋白蛋白,重组小鼠LIMPII


·重组小鼠TGF-beta RII(C端含His标签)
编号：JN1461
英文名称：Recombinant Mouse Transforming Growth Factor-beta Receptor Type II
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ile24-Asp159在C端含有His标签。

TGF-beta RII质量控制：＞95%(还原性SDS-PAGE)

TGF-beta RII制剂：冻干品

TGF-beta RII保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

TGF-beta RII复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于TGF-beta RII：
Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinity cell surface receptors: TGF-β receptor type I (TGF-β-RI), TGF-β receptor type II (TGF-β-RII), and TGF-ββ receptor type III (TGF-β-RIII). TGF-β RII is consists of a C-terminal protein kinase domain and an N-terminal ectodomain and belongs to transforming growth factor-beta (TGF-β) receptor subfamily. TGF-β RII has a protein kinase domain which can form a heterodimeric complex with another receptor protein and bind TGF-beta. This receptor/ligand complex phosphorylates protein will enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation.


JN1550型重组小鼠溶酶体整合膜蛋白(LIMPII)(SR-B2)打折促销关键词：JN1550,重组小鼠SR-B2,重组小鼠溶酶体整合膜蛋白,重组小鼠溶酶体整合膜蛋白蛋白,重组小鼠LIMPII


·重组人连接黏附分子A(JAM-A)
编号：JN0577
英文名称：Recombinant Human Junctional Adhesion Molecule A
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ser28-Val238在C端含有His标签。

JAM-A质量控制：＞95%(还原性SDS-PAGE)

JAM-A制剂：冻干品

JAM-A保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

JAM-A复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于JAM-A：
Junctional Adhesion Molecule A (JAM-A) is a single-pass type I membrane protein that belongs to the immunoglobulin superfamily. JAM-A contains 2 Ig-like V-type (immunoglobulin-like) domains and Interacts with the ninth PDZ domain. JAM-A is localized to the tight junctions of both epithelial and endothelial cells. JAM-A seems to be involved in epithelial tight junction formation. JAM-A appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM-A, thereby preventing tight junction assembly. JAM-A plays a role in regulating monocyte transmigration involved in regulating integrity of the epithelial barrier. In the case of orthoreovirus infection, JAM-A serves as receptor for the virus.

我公司正在火爆促销分子生物学试剂系列产品，欢迎您的垂询选购JN1550型重组小鼠溶酶体整合膜蛋白(LIMPII)(SR-B2)打折促销。