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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
冷藏
- 保质期:
长期
- 英文名:
Recombinant Mouse Follistatin-like Protein 1
- 库存:
694
- 供应商:
北京百奥莱博科技有限公司
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专注于生命科学和生物技术领域,致力于为客户提供包括JN1504型重组小鼠卵泡抑素样蛋白1(FSTL1)(C端带His标签)库存在内的一系列分子生物学试剂产品,并提供一系列相关的技术服务。
名称:JN1504型重组小鼠卵泡抑素样蛋白1(FSTL1)(C端带His标签)库存
规格:10μg|50μg|500μg|1mg
英文名:Recombinant Mouse Follistatin-like Protein 1
产地:国产|进口
编号:JN1504
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Glu19-Ile306在C端含有His标签。
Follistatin-like 1/FSTL1 质量控制:>95%(还原性SDS-PAGE)
Follistatin-like 1/FSTL1 制剂:冻干品
Follistatin-like 1/FSTL1 保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
Follistatin-like 1/FSTL1 复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于Follistatin-like 1/FSTL1 :
Follistatin-like 1 (FSTL1) is a secreted glycoprotein that has been grouped into the follistatin family of proteins. FSTL1 is composed of a follistatin domain and two non-functional calcium-binding motifs. It was originally cloned as a TGFβ1 inducible factor but subsequently shown to regulate diverse developmental pathways and tissue homeostasis. Ablation of the FSTL1 gene in the mouse results in several structural developmental defects and neonatal lethality due to respiratory failure. FSTL1 suppresses BMP signaling, but the precise mechanism of its action has not been elucidated. FSTL1 is expressed in the human placenta, mainly in extravillous trophoblasts.
想要了解更多关于JN1504型重组小鼠卵泡抑素样蛋白1(FSTL1)(C端带His标签)库存的价格、品牌、厂家、说明书、促销信息,请和我们联系。此外我公司还销*(代"售")下面的产品:
·重组人E26转录因子1(转录因子ETS-1)(ETS1)
编号:JN0956
英文名称:Recombinant Human E26 Transformation-Specific 1
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Thr272在N端含有His标签。
ETS1质量控制:>95%(还原性SDS-PAGE)
ETS1制剂:冻干品
ETS1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
ETS1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于ETS1:
ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or repressors of numerous genes. They are involved in stem cell development, cell senescence and death, and tumorigenesis. ETS1 is a transcription factor, containing one ETS DNA-binding domain and one PNT (pointed) domain. it has been shown to interact with TTRAP, UBE2I and Death Associated Protein 6.
JN1504型重组小鼠卵泡抑素样蛋白1(FSTL1)(C端带His标签)库存关键词:JN1504,重组小鼠FSTL1,重组小鼠卵泡抑素样蛋白1,C端带His标签,重组小鼠卵泡抑素样蛋白1蛋白
·重组人FGF9(成纤维生长因子9)
编号:JN0230
英文名称:Recombinant Human Fibroblast Growth Factor 9
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备,目的基因编码的Met1-Ser208表达纯化而来。
FGF-9质量控制:>95%(还原性SDS-PAGE)。
FGF-9制剂:冻干品
FGF-9保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
FGF-9复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于FGF-9:
Fibroblast Growth Factor 9 (FGF-9) belongs to the Fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-9 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. In addition, FGF-9 may have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.
JN1504型重组小鼠卵泡抑素样蛋白1(FSTL1)(C端带His标签)库存关键词:JN1504,重组小鼠FSTL1,重组小鼠卵泡抑素样蛋白1,C端带His标签,重组小鼠卵泡抑素样蛋白1蛋白
·重组人PGK1(磷酸甘油酸激酶1)
编号:JN1254
英文名称:Recombinant Human Phosphoglycerate kinase 1
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ser2-Ile417在C端含有His标签。
PGK1质量控制:>95%(还原性SDS-PAGE)
PGK1制剂:液体
PGK1保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于PGK1:
PGK1 is called phosphoglycerate kinase that involved in a critical energy-producing process known as glycolysis. Phosphoglycerate kinase helps carry out a chemical reaction that converts a molecule called 1,3-diphosphoglycerate, which is produced during the breakdown of glucose, to another molecule called 3-phosphoglycerate during glycolysis. PGK1 The encoded protein may also act as a cofactor for polymerase alpha.. The protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions.
我公司强烈推荐分子生物学试剂系列产品,热情期待您的咨询选购JN1504型重组小鼠卵泡抑素样蛋白1(FSTL1)(C端带His标签)库存。
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文献和实验内源性FSTL1 通过激活钠‐钾泵引起膜超极化调节痛觉信息传递
‐钾泵活性;然而,人体内是否存在钠‐钾泵的内源性的激动剂还不清楚。 近日,中科院上海生科院神经所张旭实验室通过对背根神经节(dorsal root ganglion,DRG)的研究,发现在 DRG 中有一种选择性高表达的蛋白——滤泡素抑制素样蛋白 1(Follistatin‐like 1,FSTL1)能通过清亮小泡运输至脊髓内的传入神经末端释放,并直接与传入神经末端突触前膜上的钠‐钾泵 α1 亚基相结合,增强钠‐钾泵活性,使细胞膜超极化,从而对传入神经末端的兴奋性突触传递起抑制
。当某一个标签的使用,一是能构成表位利于纯化和检测;二是构成独特的结构特征(结合配体)利于纯化。组氨酸残基侧链与固态的镍有强烈的吸引力,可用于固定化金属螯合层析(IMAC),对重组蛋白进行分离纯化。使用His-tag有下面优点:1.标签的分子量小,只有~0.84KD,而GST和蛋白A分别为~26KD和~30KD,一般不影响目标蛋白的功能;2.His标签融合蛋白可以在非离子型表面活性剂存在的条件下或变性条件下纯化,前者在纯化疏水性强的蛋白得到应用,后者在纯化包涵体蛋白时特别有用,用高浓度的变性剂溶解
)利于纯化。组氨酸残基侧链与固态的镍有强烈的吸引力,可用于固定化金属螯合层析(IMAC),对重组 蛋白进行分离纯化。使用His-tag有下面优点: 标签的分子 量小,只有~0.84KD,而GST和蛋白A分别为~26KD和~30KD,一般不影响目标蛋白的功能; His标签融合蛋白可以在非离子型表面活性剂存在的条件下或变性条件下纯化,前者在纯化疏水性强的蛋白得到应用,后者在纯化包涵体蛋白时特别有用,用高浓度的变性剂溶解后通过金属螯和亲和层析 去除杂蛋白,使复性不受其它蛋白
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