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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
冷藏
- 保质期:
长期
- 英文名:
Recombinant Mouse Serine Protease Inhibitor-clade D1
- 库存:
622
- 供应商:
北京百奥莱博科技有限公司
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专注于生命科学和生物技术领域,致力于为客户提供包括重组小鼠Serpin D1(丝*酸蛋白酶抑制剂D1) 分子生物学试剂在内的一系列分子生物学试剂产品,并提供一系列相关的技术服务。
名称:重组小鼠Serpin D1(丝*酸蛋白酶抑制剂D1) 分子生物学试剂
编号:JN1455
规格:10μg|50μg|500μg|1mg
英文名:Recombinant Mouse Serine Protease Inhibitor-clade D1
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Glu24-Ser478在C端含有His标签。
Serpin D1质量控制:>95%(还原性SDS-PAGE)
Serpin D1制剂:冻干品
Serpin D1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
Serpin D1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于Serpin D1:
SerpinD1, also known as heparin cofactor II(HC-II), is a member of Serpin superfamily of the serine proteinase inhibitors. It is a single chain glycoprotein with a size of 66.5 kDa and is secreted from hepatocytes. HC-II acts as a thrombin inhibitor in the coagulation cascade, in a glycosaminoglycan-dependent pathway using the release of a sequestered hirudin-like N-terminal tail for interaction with thrombin. This serpin belongs to multiple member group V2 of vertebrate serpin classification. It has been suggested that HC-II is a predictor of decreased atherosclerosis in the elderly and protective against atherosclerosis in mice. HCII can used as a predictive biomarker and therapeutic target for atherosclerosis.
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重组小鼠Serpin D1(丝*酸蛋白酶抑制剂D1) 分子生物学试剂关键词:重组小鼠Serpin D1,重组小鼠丝*酸蛋白酶抑制剂D1,JN1455,重组小鼠Serpin D1蛋白,重组Serpin D1
·重组人白介素IL-7(白细胞介素7)
编号:JN0349
英文名称:Recombinant Human Interleukin-7
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备,目的基因编码的Asp26-His177表达纯化而来。
IL-7质量控制:>95%(还原性SDS-PAGE)。
IL-7制剂:冻干品
IL-7保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
IL-7复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于IL-7:
Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. Human IL7 cDNA encodes a 177 amino acid precursor protein containing a 25 amino acid signal peptide and a 152 amino acid mature protein. Human and mouse IL7 share 65% sequence identity in the mature region and both exhibit cross-species activity. IL-7 signals via IL-7 receptor (IL7R) activating multiple pathways including JaK/STAT and PI3K/AKT, which regulate lymphocyte survival, glucose uptake, proliferation, and differentiation. IL-7 is also associated with cytoplasmic IL2-R gamma for signal transduction.
重组小鼠Serpin D1(丝*酸蛋白酶抑制剂D1) 分子生物学试剂关键词:重组小鼠Serpin D1,重组小鼠丝*酸蛋白酶抑制剂D1,JN1455,重组小鼠Serpin D1蛋白,重组Serpin D1
·重组人EphA8
编号:JN1372
英文名称:Recombinant Human Ephrin type A receptor 8
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ala28-Leu495在C端带有Fc标签。
EphA8质量控制:>95%(还原性SDS-PAGE)
EphA8制剂:冻干品
EphA8保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
EphA8复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于EphA8:
Ephrin type-A receptor 8 (EPHA8) is single-pass type I membrane protein. As receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation. During development of the nervous system plays also a role in axon guidance. Downstream effectors of the EPHA8 signaling pathway include FYN which promotes cell adhesion upon activation by EPHA8 and the MAP kinases in the stimulation of neurite outgrowth.
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