重组人泛素结合酶E2-V1(UBCE2V1)优惠价

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北京百奥莱博专业生产销*(代"售")重组人泛素结合酶E2-V1(UBCE2V1)优惠价，我公司供应的分子生物学试剂品类齐全，且具有优势价格，欢迎新老客户垂询订购。

名称：重组人泛素结合酶E2-V1(UBCE2V1)优惠价
品牌：百奥莱博
规格：10μg|50μg|500μg|1mg
编号：JN1030
英文名：Recombinant Human Ubiquitin-Conjugating Enzyme E2 Variant 1
产地：国产|进口
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Ala2-Asn147在C端含有His标签。

UBE2V1质量控制：＞95%(还原性SDS-PAGE)

UBE2V1制剂：液体

UBE2V1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于UBE2V1：
Ubiquitin-Conjugating Enzyme Variant 1a (UBE2V1) is a member of the Ubiquitin-conjugating (E2) enzyme family. The E2 catalytic core domain of UBE2V1 lacks an active site cysteine residue, rendering it catalytically inactive on its own. However, in the cytoplasm UBE2V1 is able to form a catalytically active complex with UBE2N/Ubc13, which mediates the synthesis Lys63-linked Ubiquitin chains and is required for NF-kappa B activation. UBE2V1 is required for UBE2N (Ubc13)/UBE2V1 Complex-dependent Lys63-linked Ubiquitin chain formation. More specifically, UBE2V1 orients the Ubiquitin molecule to favor linkage at Lys63 via a non-covalent interaction with the Ubiquitin molecule. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through Lys63. This type of poly-ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. UBE2V1 plays a role in the activation of NF-kappa-B mediated by IL1B, TNF, TRAF6, and TRAF2. It mediates transcriptional activation of target genes. UBE2V1 also controls the progress through the cell cycle and differentiation, the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.

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重组人泛素结合酶E2-V1(UBCE2V1)优惠价关键词：重组人UBCE2V1,重组人泛素结合酶E2-V1,重组泛素结合酶E2-V1,重组人泛素结合酶E2-V1蛋白,JN1030


·重组人ALDH1A2(醛脱*酶家族1成员A2)
编号：JN1546
英文名称：Recombinant Human Aldehyde dehydrogenase family 1 member A2
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Ser518在N端含有His标签。

ALDH1A2质量控制：＞95%(还原性SDS-PAGE)

ALDH1A2制剂：液体

ALDH1A2保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于ALDH1A2：
Aldehyde dehydrogenase 1 family member A2 (ALDH1A2), also known as retinaldehyde dehydrogenase 2 (RALDH2), belongs to the aldehyde dehydrogenase family which contains two members, the ALDH1 s (ALDH1A1, ALDH1A2 and ALDH1A3) and the 9-cis retinaldehyde dehydrogenase ALDH8 s. ALDH1A2 is key enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. RA is a paracrine hormone signaling molecule that functions in developing and adult tissues. ALDH1A2 was also found to regulate normal and tumor cell growth and differentiation. Several studies showed that ALDH1A2 expression is increased after the appearance of AraC resistance in clinical cases which means this protein is effective in AraC resistance.


重组人泛素结合酶E2-V1(UBCE2V1)优惠价关键词：重组人UBCE2V1,重组人泛素结合酶E2-V1,重组泛素结合酶E2-V1,重组人泛素结合酶E2-V1蛋白,JN1030

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