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- 详细信息
- 技术资料
- 保存条件:
冷藏
- 保质期:
长期
- 英文名:
Recombinant Human Caspase-10
- 库存:
382
- 供应商:
北京百奥莱博科技有限公司
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专注于生命科学和生物技术领域,致力于为客户提供包括重组人Caspase-10(CASP10)厂家直销在内的一系列分子生物学试剂产品,并提供一系列相关的技术服务。
名称:重组人Caspase-10(CASP10)厂家直销
编号:JN1004
产地:国产|进口
品牌:百奥莱博
英文名:Recombinant Human Caspase-10
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Val220-Ile480在C端含有His标签。
CASP10质量控制:>95%(还原性SDS-PAGE)
CASP10制剂:液体
CASP10保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于CASP10:
Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granzyme B and autocatalytic activity generate the two active subunits: Caspase-10 subunit p23/17, Caspase-10 subunit p12. Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the execution-phase of cell apoptosis, the initiation and execution. Human caspases can be subdivided into three functional groups: cytokine activation (caspase-1, -4, -5, and -13), apoptosis initiation (caspase-2, -8, -9, -and -10), and apoptosis execution (caspase-3, -6, and -7). CASP10 cleaves and activates caspases 3 and 7, but itself is processed by caspase 8. Defects in CASP10 are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome.
想要了解更多关于重组人Caspase-10(CASP10)厂家直销的价格、品牌、厂家、说明书、促销信息,请和我们联系。此外我公司还销*(代"售")下面的产品:
·重组人酰基蛋白硫酯酶2(LYPLA2)
编号:JN0951
英文名称:Recombinant Human Acyl-Protein Thioesterase 2
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Val231在C端含有His标签。
LYPLA2质量控制:>95%(还原性SDS-PAGE)
LYPLA2制剂:液体
LYPLA2保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于LYPLA2:
Acyl-Protein Thioesterase 2 is a cytoplasmic protein that belongs to the AB Hydrolase 2 family. LYPLA2 is a lysophospholipase and hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. LYPLA2 has hydrolase activity that converts Palmitoyl-protein to palmitate and protein. LYPLA2 regulates the multifunctional lysophospholipids by acting on biological membranes. LYPLA2 participates in Glycerophospholipid metabolism pathway, fatty acid metabolic process and lipid metabolic process.
·重组小鼠IFN-gamma R1(CD119)(C端含His标签)
编号:JN1411
英文名称:Recombinant Mouse Interferon gamma Receptor 1
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ala26-Asp253在C端含有His标签。
IFN-gamma R1/CD119质量控制:>95%(还原性SDS-PAGE)
IFN-gamma R1/CD119制剂:冻干品
IFN-gamma R1/CD119保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
IFN-gamma R1/CD119复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于IFN-gamma R1/CD119:
The tetrameric receptor complex for IFNγ consists of two subunits, IFNGR1 (IFNγ Rα) and IFNGR2 (IFNγ Rβ), through which the dimeric IFN-γ exerts its biological functions, including antiviral, antiproliferation and immune-modulatory activity in mammals. Both IFNGR1 and IFNGR2 are single transmembrane proteins belonging to the class II cytokine family. FNGR1, widely expressed in most host cells, is essential for IFNγ binding, receptor trafficking, and signal transduction. IFNGR1 possesses an intracellular Janus tyrosine kinase (JAK) 1 binding site, a signal transducer and activator of transcription 1 (STAT1) binding site. The resulting STAT1 homodimers translocate from the cytoplasm to the nucleus and bind to the interferon-gamma activated sequence (GAS) promoter to induce expression of downstream interferon stimulated genes (ISGs).
重组人Caspase-10(CASP10)厂家直销关键词:重组人Caspase-10,重组人Caspase-10蛋白,重组Caspase-10,JN1004,重组人CASP10
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重组人Caspase-10(CASP10)厂家直销关键词:重组人Caspase-10,重组人Caspase-10蛋白,重组Caspase-10,JN1004,重组人CASP10
·重组人PRCP(溶酶体Pro-X羧肽酶)
编号:JN1742
英文名称:Recombinant Human Lysosomal Pro-X Carboxypeptidase
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Leu22-His496在C端含有His标签。
PRCP质量控制:>95%(还原性SDS-PAGE)
PRCP制剂:液体
PRCP保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于PRCP:
Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, and kidney. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH. PRCP has been shown to be an activator of the cell matrix-associated prekallikrein.
我公司生产供应销*(代"售")的分子生物学试剂产品正全系列现货促销,满分期待您的垂询选购重组人Caspase-10(CASP10)厂家直销。
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