JN0973型重组小鼠聚集素(Clusterin)销售

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专业生产供应JN0973型重组小鼠聚集素(Clusterin)销*(代"售")，我公司销*(代"售")全品类的分子生物学试剂，价格优惠，欢迎广大科研工作者垂询订购。

名称：JN0973型重组小鼠聚集素(Clusterin)销*(代"售")
产地：国产|进口
规格：10μg|50μg|500μg|1mg
英文名：Recombinant Mouse Clusterin
编号：JN0973
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Glu22-Glu448在C端含有His标签。

Clusterin/CLU质量控制：＞95%(还原性SDS-PAGE)

Clusterin/CLU制剂：冻干品

Clusterin/CLU保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Clusterin/CLU复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Clusterin/CLU：
Clusterin(CLU) is a secreted protein which belongs to the clusterin family. Itis also a 75 - 80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. Clusterin is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimers disease. Its major form, a heterodimer, is secreted and present in physiological fluids, but truncated forms targeted to the nucleus have also been identified. It is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stress-induced secreted chaperone protein, amongst others.

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JN0973型重组小鼠聚集素(Clusterin)销*(代"售")关键词：重组小鼠Clusterin,重组聚集素,JN0973,重组小鼠聚集素,重组小鼠聚集素蛋白


·重组人PGD(6-磷酸葡萄糖酸脱*酶)
编号：JN1271
英文名称：Recombinant Human 6-phosphogluconate dehydrogenase
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Met1-Ala483在C端含有His标签。

PGD质量控制：＞95%(还原性SDS-PAGE)

PGD制剂：液体

PGD保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于PGD：
6-phosphogluconate dehydrogenase(PGD) is a cytoplasm-located protein, and belongs to the 6-phosphogluconate dehydrogenase family. 6PGD is the second dehydrogenase in the pentose phosphate shunt. It catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH. Mutations within the gene coding this enzyme result in 6-phosphogluconate dehydrogenase deficiency, an autosomal hereditary disease effecting the red blood cells.

·重组人HER2(ERBB2)
编号：JN1886
英文名称：Recombinant Human Receptor tyrosine-protein kinase ErbB-2
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Thr23-Thr652在C端带有Fc标签。

HER2/ERBB2质量控制：＞95%(还原性SDS-PAGE)

HER2/ERBB2制剂：冻干品

HER2/ERBB2保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

HER2/ERBB2复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于HER2/ERBB2：
Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and differentiation. HER2 has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on. HER2 is activated by dimerization and not activated by EGF, TGF-alpha and amphiregulin. Interaction with PTK6 increases its intrinsic kinase activity.It is heterodimer with EGFR, ERBB3 and ERBB4. HER2 associates with the 5-TCAAATTC-3 sequence in the PTGS2/COX-2 promoter and activates its transcription. It implicated in transcriptional activation of CDKN1A and the function of the protein involves STAT3 and SRC. And also it involved in the transcription of rRNA genes by RNA Pol I and enhances protein synthesis and cell growth.


JN0973型重组小鼠聚集素(Clusterin)销*(代"售")关键词：重组小鼠Clusterin,重组聚集素,JN0973,重组小鼠聚集素,重组小鼠聚集素蛋白


·重组人促分泌素
编号：JN0715
英文名称：Recombinant Human Secretagogin
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Met1-Pro276在C端含有His标签。

Secretagogin质量控制：＞95%(还原性SDS-PAGE)

Secretagogin制剂：冻干品

Secretagogin保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Secretagogin复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Secretagogin：
Secretagogin (SCGN) is a secreted calcium-binding protein that is found in the cytoplasm; a small proportion is associated with secretory granules and membrane fractions. SCGN contains six EF-hand domains, related to calbindin D-28K and calretinin. SCGN is thought to be involved in KCL-stimulated calcium flux and cell proliferation SCGN can be detected in human serum after ischemic neuronal damage. SCGN may function to negatively control growth and differentiation rates and, thus, indirectly inhibit cell replication.

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