重组人CDKN1A(p21细胞周期蛋白依赖性激酶4抑制剂1A

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专业生产销*(代"售")重组人CDKN1A(p21细胞周期蛋白依赖性激酶4抑制剂1A)价格厂家，我公司供应的分子生物学试剂品类齐全，且具有优势价格，欢迎新老客户垂询订购。

名称：重组人CDKN1A(p21细胞周期蛋白依赖性激酶4抑制剂1A)价格厂家
产地：国产|进口
品牌：百奥莱博
英文名：Recombinant Human p21 Cyclin Dependent Kinase 4 Inhibitor 1A
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Ser2-Pro164在C端含有His标签。

CDKN1A质量控制：＞95%(还原性SDS-PAGE)

CDKN1A制剂：冻干品

CDKN1A保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CDKN1A复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CDKN1A：
Cyclin-Dependent Kinase Inhibitor 1 (CDKN1A) is a member of the CDI family. CDKN1A is widely expressed in all adult tissues, but low expressed in the brain tissue. CDKN1A can be induced by p53/TP53, mezerein and IFNB1, repressed by HDAC1. CDKN1A may be an important intermediate, by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage, CDKN1A can bind to and inhibit cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.

关于重组人CDKN1A(p21细胞周期蛋白依赖性激酶4抑制剂1A)价格厂家的更详细说明，请致电我公司咨询，我们将以最饱满的热情为您提供解答，此外，我公司专业供应下列产品：
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重组人CDKN1A(p21细胞周期蛋白依赖性激酶4抑制剂1A)价格厂家关键词：重组人CDKN1A蛋白,重组CDKN1A,重组人p21细胞周期蛋白依赖性激酶4抑制剂1A,JN0911


·重组人趋化因子CCL23(Ckβ8-1)
编号：JN0297
英文名称：Recombinant Human C-C Motif Chemokine 23
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备，目的基因编码的Arg22-Asn120表达纯化而来。

CCL23/Ck beta 8-1质量控制：＞95%(还原性SDS-PAGE)。

CCL23/Ck beta 8-1制剂：冻干品

CCL23/Ck beta 8-1保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

CCL23/Ck beta 8-1复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于CCL23/Ck beta 8-1：
Human Chemokine (C-C Motif) Ligand 23 (CCL23) is a small cytokine belonging to the CC chemokine family. CCL23 is also known as myeloid progenitor inhibitory factor MPIF-1, CK8 and SCYA23. CCL23 cDNA encodes a 120 amino acid residue precursor protein with a putative 21 amino acid residue signal peptide that is cleaved to generate a 99 amino acid residue mature CCL23 (amino acids 22 -120). Additional N-terminal Processing of the 99 amino acid residue variant can generate a 75 amino acid residue peptide (amino acid 46-120) that is significantly more active than the 99 amino acid residue variant. CCL23 binds to CCR1 with high affinity and has chemotactic activity for monocytes, dendritic cells, and osteoclast precursors. CCL23 enhances angiogenesis of endothelial cells, but reduces the proliferation of progenitor cells giving rise to granulocyte and monocyte lineages.


重组人CDKN1A(p21细胞周期蛋白依赖性激酶4抑制剂1A)价格厂家关键词：重组人CDKN1A蛋白,重组CDKN1A,重组人p21细胞周期蛋白依赖性激酶4抑制剂1A,JN0911


·重组人泛素结合酶E2-M(UBCE2M)
编号：JN1036
英文名称：Recombinant Human Ubiquitin-conjugating Enzyme E2M
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Lys183表达纯化得来。

UBE2M质量控制：＞95%(还原性SDS-PAGE)

UBE2M制剂：液体

UBE2M保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于UBE2M：
UBE2M is a member of the E2 ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin. UBE2M accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. It involved in cell proliferation and is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation.

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