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北京现货重组人CRTAM厂家

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  • ¥180 - 1850
  • 百奥莱博
  • 北京
  • JN0518-IMY
  • 2025年07月12日
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    • 英文名

      Recombinant Human Cytotoxic and Regulatory T-Cell Molecule

    • 库存

      207

    • 供应商

      北京百奥莱博科技有限公司

    特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。

    北京百奥莱博专注于生命科学和生物技术领域,致力于为客户提供包括北京现货重组人CRTAM厂家在内的一系列分子生物学试剂产品,并提供一系列相关的技术服务。


    名称:北京现货重组人CRTAM厂家
    品牌:百奥莱博
    英文名:Recombinant Human Cytotoxic and Regulatory T-Cell Molecule
    产地:国产|进口
    编号:JN0518
    规格:10μg|50μg|500μg|1mg
    本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ser18-Ser286在C端含有His标签。

    CRTAM质量控制:>95%(还原性SDS-PAGE)

    CRTAM制剂:冻干品

    CRTAM保存
    冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
    复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。

    CRTAM复溶
    打开试剂管前请先离心。
    复溶浓度推荐大于100 μg/ml。
    冻干蛋白请溶于ddH2O。
    复溶后,请根据用量分装冻存,避免反复冻融。

    关于CRTAM
    Cytotoxic and Regulatory T-Cell Molecule (CRTAM) is a member of Nectin family under the immunoglobulin superfamily that is expressed by activated CD8+ and NK T cells. CRTAM is found in spleen, thymus, small intestine, peripheral blood, and it is highly expressed by Purkinje cells of the cerebellum. CRTAM is a type I transmembrane glycoprotein containing one Ig-like C2-type domain and one Ig-like V-type domain in its extracellular domain, while its cytoplasmic region shows a potential class I PDZ domain. CRTAM is expressed as a homodimer on the cell surface but does not show homotypic binding in trans. The high affinity of CRTAM/IGSF4 adhesion allows CRTAM to disrupt IGSF4 homotypic interactions. IGSF4 and T cell receptor coengagement of CD8+ cells expressiong CRTAM induces increased IFNγ or IL-22 production.

    北京现货重组人CRTAM厂家正在火爆热销,除此之外,为您推荐下别热销产品:

    ·重组小鼠CA14
    编号:JN1399
    英文名称:Recombinant Mouse Carbonic anhydrase 14
    规格:10μg|50μg|500μg|1mg
    本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Ala16-Met290在N端含有His标签。

    CA14质量控制:>95%(还原性SDS-PAGE)

    CA14制剂:液体

    CA14保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。

    关于CA14
    Mouse Ca14,also known as Carbonic anhydrase 14,is a member of large family of zinc metalloenzymes .It could catalyze reversible hydration of carbon dioxide. The reaction is fundamental to many processes such as respiration, renal tubular acidification and bone resorption. Fifteen CA isoforms have been reported so far. They have different patterns of tissue-specific expression and physiologic roles. Some CAs may serve as markers for tumors and hypoxia. CA XIV is a polypeptide consisting of an extracellular N-terminal catalytic domain, a membrane-spanning segment and a short intracellular C- terminal segment with several potential phosphorylation sites. A subset of CAs lack CA activity due to point mutations but retain esterase function. CA14 is widely expressed in the central nervous system


    北京现货重组人CRTAM厂家关键词:JN0518,重组CRTAM,重组人CRTAM蛋白,百奥莱博,Recombinant Human Cytotoxic and Regulatory T-Cell


    ·重组VEGF(血管内皮生长因子)
    编号:JN1305
    英文名称:Recombinant Rabbit vegf
    规格:10μg|50μg|500μg|1mg
    本品由我们的哺乳动物表达系统制备而成(人类细胞),目的蛋白包含序列() of Human vegf 在C端含有His标签。

    vegf质量控制:>95%(SEC-HPLC,还原性SDS-PAGE)


    vegf制剂:冻干品

    vegf保存
    冻干蛋白长期保存应置于-20℃以下,常温可稳定保存3周。
    复溶蛋白溶液可在4℃保存2~7天。
    复溶后的蛋白溶液应尽量避免反复冻融,可根据使用量分装冻存在-20℃以下长达3个月。

    vegf复溶
    打开试剂管前请先离心。
    复溶浓度推荐大于100 μg/ml。
    Dissolve the lyophilized protein in 1X PBS.
    复溶后,请根据用量分装冻存,避免反复冻融。

    关于vegf
    Vascular endothelial growth factor (VEGF) also known as vascular permeability factor (VPF) is a signal protein produced by cells that stimulates vasculogenesis and angiogenesis. Two receptor tyrosine kinases have been described as putative VEGF receptors. Flt-1 (fms-like tyrosine kinase), and KDR (kinase-insert-domain-containing receptor) proteins have been shown to bind VEGF with high affinity. In vitro, VEGF is a potent endothelial cell mitogen. In cultured endothelial cells, VEGF can activate phospholipase C and induce rapid increases of free cytosolic Ca2+. VEGF has been shown to stimulate von Willebrand factor release from endothelial cells and induce expression of tissue factor activity in endothelial cells as well as in monocytes. VEGF has also been shown to be chemotactic for monocytes and osteoblasts. In vivo, VEGF can induce angiogenesis as well as increase microvascular permeability. As a vascular permeability factor, VEGF acts directly on the endothelium and does not degranulate mast cells. It promotes extravasation of plasma fibrinogen, leading to fibrin deposition which alters the tumor extracellular matrix.


    北京现货重组人CRTAM厂家关键词:JN0518,重组CRTAM,重组人CRTAM蛋白,百奥莱博,Recombinant Human Cytotoxic and Regulatory T-Cell

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    我公司正在火爆促销分子生物学试剂系列产品,欢迎您的垂询选购北京现货重组人CRTAM厂家

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