北京现货重组人TNF-α(C端His标签)折扣价

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专业生产销*(代"售")北京现货重组人TNF-α(C端His标签)折扣价，我公司供应的分子生物学试剂品类齐全，且具有优势价格，欢迎新老客户垂询订购。

名称：重组人TNF-α(C端His标签)
英文名：Recombinant Human Tumor Necrosis Factor alpha
产地：国产|进口
规格：10μg|50μg|500μg|1mg
品牌：百奥莱博
编号：JN0467
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Val77-Leu233在C端含有His标签。

TNF-alpha质量控制：＞95%(还原性SDS-PAGE)

TNF-alpha制剂：冻干品

TNF-alpha保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

TNF-alpha复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于TNF-alpha：
Tumor Necrosis Factor-α (TNF-α) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressing CD4 secrete TNF-α while cells that express CD8 secrete little or no TNF-α. Synthesis of TNF-α can be induced by many different stimuli including interferons, IL2, and GM-CSF. The clinical use of the potent anti-tumor activity of TNF-α has been limited by the proinflammatory side effects such as fever, dose-limiting hypotension, hepatotoxicity, intravascular thrombosis, and hemorrhage. Designing clinically applicable TNF-α mutants with low systemic toxicity has been of intense pharmacological interest. Human TNF-α that binds to murine TNF-R55 but not murine TNF-R7, exhibits retained anti-tumor activity and reduced systemic toxicity in mice comp*(代"a")red with murine TNF-α, which binds to both murine TNF receptors. Based on these results, many TNF-α mutants that selectively bind to TNF-R55 have been designed. These mutants displayed cytotoxic activities on tumor cell lines in vitro and have exhibited lower systemic toxicity in vivo. Recombinant Human TNF-α High Active Mutant differs from the wild-type by amino acid subsitution of amino acids 1-7 with Arg8, Lys9, Arg10 and Phe157. This mutant form has been shown to have increased activity with less inflammatory side effects in vivo.

关键词：C端His标签,JN0467,重组人TNF-α蛋白,重组TNF-α


北京现货重组人TNF-α(C端His标签)折扣价极具性价比，此外，我公司正火爆促销以下产品：

 

编号	名称
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JN0247	重组人FGF2(碱性成纤维细胞生长因子2)
JN1537	重组小鼠PDGFRα(血小板衍生生长因子受体α)
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JN0683	重组人泛素结合酶E2-S(UBE2S)
JN1239	重组人COL9A1(IX型胶原蛋白α1链)
JN1217	重组人HSPB8(热休克蛋白β8)
JN0296	重组人趋化因子CCL27(CTACK)
JN1420	重组小鼠TIGIT
JN0960	重组人ABCB5(ATP结合盒蛋白亚家族B成员5)
JN0723	重组人ADPRH(ADP核糖精*酸水解酶)
JN1303	重组人Serpin B9(丝*酸蛋白酶抑制剂B9)
JN0366	重组人白介素IL-3(C端带His标签)
JN1006	重组人OBFC1(含寡核苷酸结合折叠域蛋白1)
JN1862	重组人FCGR3B
JN0779	重组人胆色素原脱*酶(HMBS)
JN1472	重组小鼠Lipocalin-2(NGAL)(C端带Fc标签)
JN0961	重组人NEDD8(神经发育下调因子8)(神经前体细胞表达发育下调蛋白8)
JN0708	重组人附睾分泌蛋白E1(NPC2)
JN0686	重组人结蛋白(Desmin)
JN1642	重组人FCER2(CD23)
JN0432	重组小鼠干扰素IFN-γ(带His标签)
JN0194	His标签抗体
JN0200	HRP标记山羊抗兔IgG(H+L)
JN2029	重组人SCO1蛋白
JN1882	重组人CD200
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JN1150	重组人SMPDL3A(酸性鞘磷脂酶如磷酸二酯酶3A)
JN1254	重组人PGK1(磷酸甘油酸激酶1)
JN1588	重组人Importinβ1(KPNB1)(核转运受体蛋白)(输入蛋白β1)
JN0193	GST标签抗体
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