- ￥630 - 2415
- Elabscience
- 湖北武汉
- E-AB-21143
- 2025年07月14日
- WB;IHC-p;ELISA
- Rabbit
- Human;Mouse;Rat;Monkey
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG
- 形态：
液体
- 保存条件：
在-20℃下储存有效期为12个月。 避免冻融循环。
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
Human;Mouse;Rat;Monkey
- 保质期：
12个月
- 目录编号：
E-AB-21143
- 级别：
科研级别
- 库存：
999
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 宿主：
Rabbit
- 应用范围：
WB;IHC-p;ELISA
- 抗体英文名：
Phospho-FLNA (Ser2152) Polyclonal Antibody
- 抗体名：
Phospho-FLNA (Ser2152) 多克隆抗体_货号:E-AB-21143_修饰性抗体
- 规格：
120μL/60μL/20μL
| 规格： | 120μL | 产品价格： | ￥2415.0 |
|---|---|---|---|
| 规格： | 60μL | 产品价格： | ￥1510.0 |
| 规格： | 20μL | 产品价格： | ￥630.0 |
Phospho-FLNA (Ser2152) 多克隆抗体产品名称：Phospho-FLNA (Ser2152) 多克隆抗体， 货号：E-AB-21143
| 已验证样本 | Western Blot（WB）已验证样本:HUVEC |
| 稀释 | WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000 |
| 克隆性 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | Synthesized peptide derived from human Filamin 1 around the phosphorylation site of Ser2152 |
| Abbre | Filamin 1 (phospho Ser2152) |
| 同义词 | ABP 280;ABP-280;Actin-binding protein 280;Alpha filamin;Alpha-filamin;APBX;CSBS;CVD1;Endothelial actin binding protein;Endothelial actin-binding protein;Filamin 1;Filamin A alpha;Filamin A;Filamin-1;Filamin-A;FLN;FLN-A;FLN1;FLNA;FLNA;FMD;MNS;NHBP;Non muscle filamin;Non-muscle filamin;OPD;OPD1;OPD2;XLVD;XMVD抗体 |
| Swissprot | P21333 |
| 计算的MW | 281kDa |
| 实测MW | 280kDa |
| 细胞定位 | Cytoplasm>cell cortex. Cytoplasm>cytoskeleton. |
| 组织特异性 | Ubiquitous. |
| 浓度 | 1 mg/mL |
| 储存方法 | 在-20℃下储存有效期为12个月。 避免冻融循环。 |
| 缓冲 | PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4 |
| 纯化方法 | Affinity purification |
| 研究领域 | Cancer; Signal Transduction |
| Conjugation | Unconjugated |
| 产品描述： | The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene. |
Phospho-FLNA (Ser2152) 多克隆抗体Elabscience®流式抗体致力于为您的流式细胞分析实验带来更优质的体验，已有3,000+指标，选用经典克隆株纯化抗体，产品涵盖抗人/大鼠/小鼠等，指标丰富。
Phospho-FLNA (Ser2152) 多克隆抗体在-20℃下储存有效期为12个月。 避免冻融循环。
Phospho-FLNA (Ser2152) 多克隆抗体产品更多产品信息查看欢迎咨询我们和搜索武汉伊莱瑞特Elabscience官网查看。
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文献和实验Using Phospho‐Motif Antibodies to Determine Kinase Substrates
the phosphorylation site; therefore, substrate?directed, phosphorylation?state?sensitive, motif?specific (?phospho?motif?) antibodies represent powerful tools to identify novel kinase substrates and to investigate mechanisms of substrate phosphorylation
), and causes activation of KOR. Agonist-activated KOR becomes a substrate for G protein receptor kinase (GRK), which phosphorylates the Ser369 residue at the C-terminal tail of the receptor in the first step in the β-Arrestin-dependent desensitization cascade
at 10, 25, and 50 μM). At 24 h post-treatment, celllysates were obtained; SDS-PAGE and Western blotting were performed as described in Section 3, Methods. AR-A014418dose-dependent decreases of phospho-β-catenin (Ser33/37) and phospho-glycogen synthase
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