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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
IgG
- 形态:
液体
- 保存条件:
在-20℃下储存有效期为12个月。 避免冻融循环。
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Human;Mouse;Rat
- 保质期:
12个月
- 目录编号:
E-AB-22086
- 级别:
科研级别
- 库存:
999
- 供应商:
武汉伊莱瑞特生物科技股份有限公司
- 宿主:
Mouse
- 应用范围:
WB;IF
- 抗体英文名:
Histone H2B Monoclonal Antibody
- 抗体名:
Histone H2B 单克隆抗体_货号:E-AB-22086_单克隆抗体
- 规格:
120μL/60μL/20μL
| 规格: | 120μL | 产品价格: | ¥2310.0 |
|---|---|---|---|
| 规格: | 60μL | 产品价格: | ¥1420.0 |
| 规格: | 20μL | 产品价格: | ¥580.0 |

Histone H2B 单克隆抗体产品名称:Histone H2B 单克隆抗体, 货号:E-AB-22086
| 已验证样本 | Western Blot(WB)已验证样本:Hela,3T3,RAW264.7,Rat brain,Rat kidney 免疫荧光(IF)已验证样本:Mouse kidney |
| 稀释 | WB 1:1000-3000, IF 1:100-200 |
| 克隆性 | Monoclonal |
| 同种型 | IgG |
| 免疫原 | Synthetic Peptide |
| Abbre | Histone H2B |
| 同义词 | HIST1H2BA;testis;bA317E16.3;H2B;H2B histone family member U;H2B histone family member U testis specific;H2B histone family;member U;(testis specific);H2B testis;H2B1A;H2BFU;H2BT;HIST1H2BA;Histone 1;H2ba;Histone cluster 1 H2ba;Histone H2B;Histone H2B testis;Histone H2B type 1 A;Histone H2B type 1-A;Histone H2B type 1A;STBP;Testis specific histone H2B;Testis-specific histone H2B;TSH 2B;TSH2B;TSH2B.1抗体 |
| Swissprot | P33778 |
| 计算的MW | 14kDa |
| 实测MW | 14kDa |
| 细胞定位 | Cytosol,Nucleus,nuclear chromosome, telomeric region,nucleoplasm,nucleus,Other locations:nucleosome |
| 浓度 | 1 mg/mL |
| 储存方法 | 在-20℃下储存有效期为12个月。 避免冻融循环。 |
| 缓冲 | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
| 纯化方法 | Protein A purification |
| 研究领域 | Cancer; Epigenetics and Nuclear Signaling |
| Clone No. | Clone:3C3 |
| Conjugation | Unconjugated |
| 产品描述: | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. HIST1H2BB (Histone Cluster 1 H2B Family Member B) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is HIST1H2BN. |

Histone H2B 单克隆抗体Elabscience®流式抗体致力于为您的流式细胞分析实验带来更优质的体验,已有3,000+指标,选用经典克隆株纯化抗体,产品涵盖抗人/大鼠/小鼠等,指标丰富。

Histone H2B 单克隆抗体在-20℃下储存有效期为12个月。 避免冻融循环。
Histone H2B 单克隆抗体产品更多产品信息查看欢迎咨询我们和搜索武汉伊莱瑞特Elabscience官网查看。
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文献和实验Histone Acetylation and Deacetylation
transcription (1 ,2 ). DNA is packaged into chromatin, a highly organized and dynamic protein-DNA complex. The fundamental subunit of chromatin, the nucleosome, is composed of an octomer of four core histones, an H3/H4 tetramer and two H2A/H2B dimers, surrounded
组蛋白是和染色体相联的最主要的蛋白质。它的作用是和染色体中的 DNA 的负电荷结合。组蛋白是比较小的碱性蛋白;在细胞正常 pH 值时,组蛋白带有正电荷,这样它们就可以和 DNA 结合,这个正电荷主要存在于碱性氨基酸 Lys 和 Arg 的 -NH3 上。其实,组蛋白约含 25% 的 Arg 和 Lys 。比其他蛋白的 Arg , Lys 的含量都多。和真核 DNA 结合的有 5 种类型的组蛋白: H1 , H2A , H2B , H3
组蛋白是真核生物染色体的基本结构蛋白, 是一类小分子碱性蛋白质, 有五种类型:H1 、H2A 、H2B 、H3 、H4,它们富含带正电荷的碱性氨基酸, 能够同DNA中带负电荷的磷酸基团相互作用。 组蛋白的基因非常保守。亲缘关系较远的种属中, 四种组蛋白(H2A、H2A、H3、H4)氨基酸序列都非常相似, 如海胆组织H3的氨基酸序列与来自小牛胸腺的H3的氨基酸序列间只有一个氨基酸的差异, 小牛胸腺的H3的氨基酸序列与豌豆的H3也只有4个氨基酸不同。不同生物的H1序列变化
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