- 询价
- 江蓝纯
- T110101
- 2025年07月14日
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- 详细信息
- 技术资料
- 保质期：
两年
- 英文名：
Tetraethylthiuram disulfide
- 库存：
99
- 供应商：
江蓝纯
- CAS号：
97-77-8
属性
| 密度 | 1.2700 |
| 熔点 | 69-71°C |
| 溶解性 | Soluble in water (4 mg/l at 25 °C), acohol (38.2 mg/ml), ether (71.4 mg/ml), chloroform, and acetonitrile |
描述
| 产品介绍 | Disulfiram is a DNA demethylating agent and DIG1 inducer which inhibits prostate cancer cell growth by inhibition of DNA methyltransferase (Dnmt). In addition, studies indicate that disulfiram inhibits aldehyde dehydrogenase (ALDH) resulting in the accumulation of acetaldehyde upon ethanol ingestion. Alternate studies show that disulfiram also inhibits dopamine β-hydroxylase (DBH), an enzyme important in converting dopamine to norepinephrine in noradrenergic neurons. Futhermore, disulfiram can reduce toxicity and carcinogenesis by inhibiting the cytochrome P450IIE1 (CYP2E1). It has been reported that disulfiram can also inhibit tumor cell growth via binding to cellular copper, which inhibits proteosome activity and induces apoptosis. Disulfiram is an inhibitor of ADH and V-ATPase |
| 别名 | 双硫伦;双硫醒;戒酒硫;双(二乙硫代氨基甲酰)二硫化物;TETD;Disulfiram; Bis(diethylthiocarbamyl) disulfide; Bis(diethylthiocarbamoyl) disulfide; TETD |
| 应用 | 醇脱氢酶抑制剂。 An ALDH and tumor cell growth inhibitor |
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二硫化四乙基秋兰姆 97%
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