- 询价
- BIO-RAD
- HCA270
- UK
- 2025年11月06日
- E
- Human
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
Trastuzumab antibody | AbD18018_hIgG4_Pro
- 抗体英文名：
HUMAN ANTI TRASTUZUMAB
- 浓度：
IgG concentration 0.5 mg/ml
- 应用范围：
E
- 宿主：
Human
- 保质期：
自发货之日起 12 个月
- 目录编号：
AbD18018_hIgG4_Pro
- 供应商：
伯乐生命医学产品（上海）有限公司
- 标记物：
Purified
- 克隆性：
Monoclonal Antibody
- 形态：
Human IgG4 antibody selected from the HuCAL phage display library and expressed in a human cell line - liquid.
- 亚型：
IgG4
- 免疫原：
Trastuzumab
- 规格：
0.1 mg
Anti-trastuzumab antibody clone AbD18018 has been converted to human IgG4 isotype to offer assay developers increased flexibility in assay design. When used as an ELISA detection antibody, a secondary anti-human IgG4 antibody is required, which can be labeled according to the requirements of the user's preferred assay platform.
The antibody can be used to develop a pharmacokinetic (PK) bridging assay to measure free drug in preclinical research and clinical trials using patient sera. Antibody clones AbD16712 (HCA166) or AbD18141 (HCA169), both monovalent Fab format, are recommended as the capture antibody. Detection can be performed using clone AbD18018_hIgG4_Pro and an HRP conjugated anti-human IgG4 secondary antibody (MCA2098P).
This clone is also available as an IgG1 isotype in both a purified unconjugated format (HCA177) and directly conjugated to HRP (HCA177P).
Trastuzumab, also known as Herceptin®, is a drug used in the treatment of HER2 postive breast cancer and other HER2 over-expressing cancers including HER2-positive metastatic cancers of the gastrointestinal tract. Trastuzumab binds to the HER2 (or c-erbB2) proto-oncogene, an EGF receptor-like protein found on 20-30% of breast cancer cells. The binding leads to antibody mediated (complement mediated) killing of the HER2 positive cells.
View a summary of all anti-trastuzumab antibodies
储存信息
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA | ✓ |
- Technical Advice
- Recommended protocols and further information about HuCAL recombinant antibody technology can be found in the HuCAL Antibodies Technical Manual.
- ELISA
- This product may be used as a detection reagent in a sandwich ELISA together with an HRP conjugated anti human IgG4 secondary antibody (MCA2098P) and HCA169 as the capture reagent.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验a simple ELISA method to detect human anti-antibody response.
Immunohistochemistry: Mouse Anti-Human MCP-1
. 4. Incubate the tissue section overnight at 4?C with Mouse Anti-Human MCP-1 at 10.0 μg/mL. Wash the slide twice for three minutes each. 5. Incubate the tissue section with the Envision HRP polymer kit (Dako) according to the manufacturer’s
Anti-HMdU Autoantibodies in Human Sera as a Biomarker of Cancer Risk
Our laboratory has discovered that blood sera of healthy men and women contain low levels of anti-HMdU (Shydroxymethyl-2′-deoxyuridine, an oxidized thymidine) autoantibodies (aAbs) (1 ,2 ) However, patients with chronic inflammatory
技术资料暂无技术资料 索取技术资料
