- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
2-8℃
- 保质期:
见包装
- 英文名:
Piperine
- 库存:
大量现货
- 供应商:
上海研谨生物
- CAS号:
94-62-2
- 规格:
20mg
胡椒碱
分析标准品,HPLC≥98%
Piperine
CAS号:94-62-2
分子式:C17H19NO3
分子量:285.34
MDL:MFCD00005839
|
货号 |
规格/参数/品牌 |
价格 |
货期 |
|
YJ-B20516-20mg |
分析标准品,HPLC≥98% |
¥180.00 |
现货 |
|
YJ-B20516-1g |
分析标准品,HPLC≥98% |
¥1320.00 |
现货 |
|
JS30603-1g |
BR,98% |
¥160.00 |
现货 |
|
JS30603-5g |
BR,98% |
¥280.00 |
现货 |
|
JS30603-25g |
BR,98% |
¥780.00 |
现货 |
|
JS30603-100g |
BR,98% |
¥1780.00 |
现货 |
|
JA10337-20mg |
分析标准品,含量98.5%,可溯源 |
¥320.00 |
现货 |
产品介绍
Piperine是从胡椒中分离的天然生物碱,可以抑制P-glycoprotein and CYP3A4的活性,在HeLa细胞中的IC50值为61.94±0.054 μg/mL。
熔点: 131-135°C(lit.)
沸点: 498.524°C at 760 mmHg
外观: 白色晶体粉末
溶解性: DMSO : 50 mg/mL (175.23 mM; Need ultrasonic)
敏感性: 对光,湿度,空气敏感
储存条件: 2-8℃
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文献和实验参考文献(18篇)
18. [IF=4.9] Dongyan Guan et al."The Extract of Piper nigrum Improves the Cognitive Impairment and Mood in Sleep-Deprived Mice Through the JAK1/STAT3 Signalling Pathway."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2025 Jan;26(5):1842
17. [IF=8.2] Kangyun Zhao et al."Investigation of the formation mechanism of the pepper starch-piperine complex."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES".2024 May;268:131777
16. [IF=5.8] Chang Yang et al."Umbilical therapy for promoting transdermal delivery of topical formulations: Enhanced effect and underlying mechanism."INTERNATIONAL JOURNAL OF PHARMACEUTICS.2024 Mar;652:123834
15. [IF=6.51] Jiawei Han et al."Mechanistic insight into gel formation of co-amorphous resveratrol and piperine during dissolution process."INTERNATIONAL JOURNAL OF PHARMACEUTICS.2023 Mar;634:122644
14. [IF=3.756] Jiawei Han et al."Self-gelation involved in the transformation of resveratrol and piperine from a co-amorphous system into a co-crystal system."CRYSTENGCOMM.2022 Jul;:
13. [IF=7.419] Baoyi Chen et al."Protective effect of oxyberberine against acute lung injury in mice via inhibiting RhoA/ROCK signaling pathway."BIOMEDICINE & PHARMACOTHERAPY.2022 Sep;153:113307
12. [IF=6.321] Yanjie Liu et al."Crystal Structure, Solubility, and Pharmacokinetic Study on a Hesperetin Cocrystal with Piperine as Coformer."Pharmaceutics. 2022 Jan;14(1):94
11. [IF=3.779] Xingming Hou et al."Natural Piperine Improves Lipid Metabolic Profile of High-Fat Diet-Fed Mice by Upregulating SR-B1 and ABCG8 Transporters."J Nat Prod. 2021;84(2):373–381
10. [IF=6.023] Maiquan Li et al."Discovery of Keap1−Nrf2 small−molecule inhibitors from phytochemicals based on molecular docking."Food Chem Toxicol. 2019 Nov;133:110758
9. [IF=2.419] Tingting Gao et al."Characterization of piperine metabolites in rats by ultra-high-performance liquid chromatography with electrospray ionization quadruple time-of-flight tandem mass spectrometry."Rapid Commun Mass Sp. 2017 Jun;31(11):901-910
8. [IF=3.046] Liwei Dong et al."Echinacoside induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1."Oncotargets Ther. 2015; 8: 3649–3664
7. [IF=5.875] Ruoning Wang et al."Involvement of metabolism-permeability in enhancing the oral bioavailability of curcumin in excipient-free solid dispersions co-formed with piperine."Int J Pharmaceut. 2019 Apr;561:9
6. Gao, Tingting, et al. "Characterization of piperine metabolites in rats by ultra‐high‐performance liquid chromatography with electrospray ionization quadruple time‐of‐flight tandem mass spectrometry." Rapid Communications in Mass Spectrometry 31.11 (2017):
5. 陆昕怡, 韩加伟, 李文,等. 姜黄素/胡椒碱固体分散体的制备及体外评价[J]. 现代中药研究与实践, 2018, 032(003):49-53.
4. 黄容, 陆昕怡, 韩加伟,等. 姜黄素-胡椒碱固体分散体的制备与生物利用度研究. 中草药.
3. 陈永昆, 姜亭亭, 吉世松,等. 胡椒碱联合硝苯地平对家兔血压的影响[J]. 临床医学研究与实践, 2017, 2(033):10-11.
2. 宋思维, 唐艳红. 胡椒碱对缺氧复氧心肌细胞的保护作用及机制研究[J]. 岭南心血管病杂志, 2019, 25(01):113-118.
1. 严玉玲, 郭焰, 豆一玲. 胡椒碱分离纯化工艺的研究[J]. 中国农业信息, 2015(17):165.
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