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RT(常温）
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- CAS号：
1797-75-7
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文献和实验Role of Nrf2-Dependent ARE-Driven Antioxidant Pathway in Neuroprotection
toxicants. The mitochondrial complex II inhibitor malonate causes striatal damage reminiscent of Huntington’s disease and is known to involve oxidative stress in its pathogenesis. In order to achieve a systemic upregulation of antioxidant
) Sodium azide 18.4 mg% (w/v) Dinitrophenol (DNP) 6.64% (w/v) Sodium Malonate 10% (w/v) KOH Procedure When you enter the lab, check that the reference chambers of the Gilson respirometer
Recommended Experiments with Isolated Mitochondria
a volume of mitochondria that produced good slopes with glutamate as substrate. Add 5 µl 0.5M succinate, confirm the slope increase. Without too much delay, add 10 µl 0.5M malonate, obtain a slope. Malonate is a competitive inhibitor. What would you expect to be the effect
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