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- 详细信息
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
Jaceosidin
- 库存:
10
- 供应商:
TargetMol
- CAS号:
18085-97-7
- 规格:
100 mg/50 mg/1 mg/25 mg/10 mg/5 mg/1 mL
| 规格: | 100 mg | 产品价格: | ¥7280.0 |
|---|---|---|---|
| 规格: | 50 mg | 产品价格: | ¥4990.0 |
| 规格: | 1 mg | 产品价格: | ¥493.0 |
| 规格: | 25 mg | 产品价格: | ¥3730.0 |
| 规格: | 10 mg | 产品价格: | ¥1830.0 |
| 规格: | 5 mg | 产品价格: | ¥1160.0 |
| 规格: | 1 mL | 产品价格: | ¥843.0 |
Product Introduction
Bioactivity
英文名:Jaceosidin
描述:Jaceosidin has anti-oxidative activity. Jaceosidin has anti-inflammatory activity, also a microglial inhibitor with anti-neuroinflammation activity. aceosidin has anticancer activity, modulates the ERK/ATM/Chk1/2 pathway, leading to inactivation of the Cdc2-cyclin B1 complex, followed by G2/M cell cycle arrest in endometrial cancer cells. Jaceosidin has immunosuppressive effect through inhibiting T cell proliferation and activation, which is closely associated with its potent down-regulation of the IFN-γ/STAT1/T-bet signaling pathway. The pharmacokinetics of Jaceosidin may be dramatically affected by polymorphic CYP1A2, UGT1A1, and UGT1A7 responsible for the metabolism of Jaceosidin or by the coadministration of relevant CYP1A2 or UGT inhibitors or inducers.

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