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Please store the product under the recommended conditions in the Certificate of Analysis.
- 库存：
货期：询盘
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MedChemExpress LLC
- CAS号：
175139-41-0
- 规格：
1 mg/5 mg
| 规格： | 1 mg | 产品价格： | ￥1980.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥4870.0 |
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CP 316311
CAS No. : 175139-41-0
MCE 国际站：CP 316311
产品活性：CP 316311 是一种有效的，选择性的 CRF1 receptor 拮抗剂，IC50 值为 6.8 nM。
研究领域：GPCR/G Protein
作用靶点：CRFR
In Vitro: CP 316311 fully antagonizes CRF-stimulated adenylate cyclase activity in rat cortex and at human CRF1 receptors endogenously expressed in IMR32 cells with apparent Ki values of 7.6 and 8.5 nM, respectively.
In Vivo: CP 316311 (3.2 mg/kg) inhibits 125I-oCRF binding by >80% in rats. CP 316311 significantly attenuates activation of the hypothalamic−pituitary−adrenal (HPA) axis, with an MED value of 10 mg/kg, p.o. CP 316311 blocks the effects of both the exogenous and endogenous CRF in the CNS. CP 316311 blocks the effects induced by the exogeneous or endogeneous CRF in the brain in rat models.
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文献和实验Isolation of CP43 and CP47 Photosystem II Proximal Antenna Complexes From Plants
A single-column method to purify the CP43 and CP47 pigment-protein complexes of photosystem (PS)II from higher plants is presented. To validate the isolation procedure, three different species were used (Spinacea oleracea, Beta vulgaris
Isolation and Purification of CP43 and CP47 Photosystem II Proximal Antenna Complexes from Plants
A method to isolate and purify CP43 and CP47 pigment–protein complexes from Photosystem (PS) II of higher plants is presented. The method has been developed in spinach, but it may also be valid for other plant species, since there is high
Using the mRNA-MS2/MS2CP-FP System to Study mRNA Transport During Drosophila Oogenesis
to visualising mRNA localisation in vivo, in which RNAs containing MS2 binding sites are labelled by the MS2 coat protein fused to fluorescent reporters. We discuss the use of this mRNA-MS2/MS2CP-FP system to study mRNA localisation during Drosophila oogenesis
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