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上海希言科学仪器有限公司
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文献和实验Drug-to-Antibody Ratio (DAR) and Drug Load Distribution by LC-ESI-MS
This chapter describes an LC-ESI-MS method for the DAR and drug load distribution analysis that is suitable for lysine-linked ADCs. The ADC sample is desalted using a reversed-phase LC column with an acetonitrile gradient prior to online
Since its introduction more than a decade ago, denaturing HPLC has been widely used to screen nuclear and mitochondrial DNA for mutations. We recently developed a quantitative method based on denaturing HPLC to measure DNA mutation load
EpsteinBarr Virus (EBV) Load Determination Using Real-Time Quantitative Polymerase Chain Reaction
for EBV viral load determination. This chapter describes the use of a laboratory-developed RQ-PCR EBV viral load assay for the detection of EBV DNA in cell-free plasma and cerebrospinal fluid samples.
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