Anti-IgM (Fc specific)

Fc受体 Fc receptor

作为免疫反应调节的细胞而发挥作用，但这些细胞的Fc受体的作用尚不甚明了。在人体，具有对IgM的Fc受体的细胞，是B细胞的助细胞，以及具有对IgG的受体细胞，是作为抑制细胞而起作用。（4）对肥大细胞的Fc受体结合的IgE，其进一步与抗原结合时，肥大细胞可释放出引起“即发型”过敏症因子。（5）非淋巴细胞性的某种细胞（K细胞），可与癌细胞同异种细胞结合的IgG的Fc部分结合，给这些细胞以障碍，这种现象称为抗体依赖性细胞障碍作用（antibody dependent cellular cytotoxi

Anti-PEG IgM Production via a PEGylated Nano-Carrier System for Nucleic Acid Delivery

their long-circulating properties when they are injected repeatedly at certain intervals in the same animal. This unexpected and undesirable phenomenon is referred to as the accelerated blood clearance (ABC) phenomenon. Anti-PEG IgM produced in response

Exploiting Fc Chimaeric Proteins for the Identification of Ligands Specific for the Mannose Receptor

. In this chapter we describe our experience in the use of proteins containing selected regions of the mannose receptor fused to the Fc region of human IgG1 or murine IgG2b. Using these reagents we have discovered new and unexpected ligands for the mannose receptor