ERN1抗体ERN1兔多抗抗体Serine/threonin
e protein kinase/endoribonuclease IRE1 antibody抗体ERN1 Antibody, FITC conjugated抗体- ￥880 - 1320
- CUSABIO
- CN
- CSB-PA007795LC01HU
- 2025年07月13日
- /
- Rabbit
- Human
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- 文献和实验
- 技术资料
- 免疫原：
Recombinant Human Serine/threonine-protein kinase/endoribonuclease IRE1 protein (493-561AA)
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
FITC
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
O75460
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
/
- 浓度：
>95%,Protein G purified
- 靶点：
ERN1
- 抗体英文名：
ERN1 Antibody, FITC conjugated
- 抗体名：
Serine/threonine protein kinase/endoribonuclease IRE1 antibody
- 规格：
100μg/50μg
| 规格： | 100μg | 产品价格： | ￥1320.0 |
|---|---|---|---|
| 规格： | 50μg | 产品价格： | ￥880.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
功能
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Ier1 p: A Kinase and Site-Specific Endoribonuclease
proteins (1 ). Perturbation of the ER lumen interferes with the production of many essential cellular components and can thus be highly deleterious. Indeed, in humans, defects in protein folding in the ER can lead to devastating diseases, such as cystic
kinases activate the serine/threonine kinases M n k l and M n k 2 . EMBO J. 16, 1909-1920. 13. Fujita, H., Fujita, H., Takemura, M., et al. (2003) A n ArabidopsisM A D S - b o x protein, A G L 2 4 , is specifically bound to and phosphorylated
TRAF‐Mediated TNFR‐Family Signaling
., Drexler, H.G., and Quentmeier, H. 2003. Tumor necrosis factor receptor‐associated factor (TRAF) 4 is a new binding partner for the p70S6 serine/threonine kinase. Leuk. Res. 27:687‐694.
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