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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant Human Tumor necrosis factor ligand superfamily member 11 protein (73-306AA)
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
Biotin
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
O14788
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA
- 浓度:
>95%,Protein G purified
- 靶点:
TNFSF11
- 抗体英文名:
TNFSF11 Antibody, Biotin conjugated
- 抗体名:
TNFSF11;OPGL;RANKL;TRANCE;Tumor necrosis factor ligand superfamily member 11;Osteoclast differentiation factor;ODF;Osteoprotegerin ligand;Receptor activator of nuclear factor kappa-B ligand;TNF-related activation-induced cytokine;CD antigen CD254
- 规格:
100μg/50μg
| 规格: | 100μg | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥880.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
功能
Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy (PubMed:22664871). Induces osteoclastogenesis by activating multiple signaling pathways in osteoclast precursor cells, chief among which is induction of long lasting oscillations in the intracellular concentration of Ca (2+) resulting in the activation of NFATC1, which translocates to the nucleus and induces osteoclast-specific gene transcription to allow differentiation of osteoclasts. During osteoclast differentiation, in a TMEM64 and ATP2A2-dependent manner induces activation of CREB1 and mitochondrial ROS generation necessary for proper osteoclast generation (By similarity).风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验(杨希峰),Yang CY(杨春瑛) et al. Generation and characterization of monoclonal antibody against HIT3a (抗CD3单克隆抗体HIT3a的制备和特异性鉴定), Acta Academiae Medicinae Sinicae (中国医学科学院学报),1993, 15:157-162.[6] Xiong D S(熊冬生),Yang C Z(杨纯正),Shao X F(邵晓枫)et al. Generation
是通过直接或间接地影响到该细胞的bcl-2的表达或功能,进而抑制细胞生长,诱导细胞凋亡,最终得以有效地挟制和杀灭肿瘤,这为抗体可用于联合化疗或降低病人耐药的临床治疗提供了有力的证据。【参考文献】[1]Golay JT,Clark EA,Beverley PC,et al. The CD20 (BP35)antigen is involved in activation of B cell from the G0 to the G1 phase of the cell cycle. J Immunol
人血小板膜糖蛋白IIbIIIa(GP-IIbIIIa/CD41+CD61)抗体
人血小板膜糖蛋白IIbIIIa(GP-IIbIIIa/CD41+CD61) 抗体 酶联免疫分析试剂盒使用说明书 本试剂仅供研究使用 目的:本试剂盒用于测定人血清,血浆及相关液体样本中血小板膜糖蛋白IIbIIIa(GP-IIbIIIa/CD41+CD61) 抗体 的含量。 实验原理: 本试剂盒应用双抗原夹心法测定标本中人血小板膜糖蛋白 IIbIIIa(GP-IIbIIIa/CD41+CD61) 抗体
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