- ￥880 - 1320
- CUSABIO
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- CSB-PA803115LC01HU
- 2025年07月16日
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant Human E3 ubiquitin-protein ligase synoviolin protein (338-487AA)
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
FITC
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
Q86TM6
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
/
- 浓度：
>95%,Protein G purified
- 靶点：
SYVN1
- 抗体英文名：
SYVN1 Antibody, FITC conjugated
- 抗体名：
SYVN1;HRD1;KIAA1810;E3 ubiquitin-protein ligase synoviolin;RING-type E3 ubiquitin transferase synoviolin;Synovial apoptosis inhibitor 1
- 规格：
100μg/50μg
| 规格： | 100μg | 产品价格： | ￥1320.0 |
|---|---|---|---|
| 规格： | 50μg | 产品价格： | ￥880.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
功能
Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates, promoting their degradation. Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Also promotes the degradation of normal but naturally short-lived proteins such as SGK. Protects cells from ER stress-induced apoptosis. Protects neurons from apoptosis induced by polyglutamine-expanded huntingtin (HTT) or unfolded GPR37 by promoting their degradation. Sequesters p53/TP53 in the cytoplasm and promotes its degradation, thereby negatively regulating its biological function in transcription, cell cycle regulation and apoptosis.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验A SENSITIVE METHOD FOR DETECTION OF APOPTOSIS BY SINGLE LASER FLOW CYTOMETRY
with single or dual-color phenotype and the use of FITC and/or PE conjugated monoclonal antibodies. Surface antigen staining is done according to standard methods before staining for apoptosis. Then, the apoptosis assay is performed as described above.
Simultaneous analysis of DNA content and surface immunophenotype using gentle ethanol fixation&
resuspended in high concentrations of fetal bovine serum, and has been thoroughly described in the literature. A second technique uses ethanol solutions in glycerol, and is still under development. Materials The fluorochrome-conjugated antibody
Simultaneous analysis of DNA content and surface
in the literature. A second technique uses ethanol solutions in glycerol, and is still under development. Materials Procedure The fluorochrome-conjugated antibody or antibodies of interest. An appropriate DNA binding
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