MAPK10抗体MAPK10兔多抗抗体Stress-acti
vated protein kinase JNK3 antibody抗体MAPK10 Antibody, Biotin conjugated抗体- ￥880 - 1320
- CUSABIO
- CN
- CSB-PA013449LD01HU
- 2025年07月15日
- ELISA
- Rabbit
- Human
企业认证
相关产品推荐更多 >
GTF2H2抗体GTF2H2兔多抗抗体TFIIH basal transcription factor complex p44 subunit antibody抗体GTF2H2 Antibody抗体
￥440
SLAMF1抗体SLAMF1一抗抗体SLAMF1 protein antibody抗体SLAMF1 Antibody抗体
￥880VAC14抗体VAC14兔多抗抗体VAC14_HUMAN antibody抗体VAC14 Antibody, Biotin conjugated抗体
￥880
B3GAT1抗体B3GAT1一抗抗体UDP-GlcUA:glycoprotein beta-1 antibody抗体B3GAT1 Antibody抗体
￥1100
CYP2C19抗体CYP2C19兔多抗抗体Xenobiotic monooxygenase antibody抗体CYP2C19 Antibody, FITC conjugated抗体
￥880
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant Human Mitogen-activated protein kinase 10 protein (133-316AA)
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
Biotin
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
P53779
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA
- 浓度：
>95%,Protein G purified
- 靶点：
MAPK10
- 抗体英文名：
MAPK10 Antibody, Biotin conjugated
- 抗体名：
Stress-activated protein kinase JNK3 antibody
- 规格：
100μg/50μg
| 规格： | 100μg | 产品价格： | ￥1320.0 |
|---|---|---|---|
| 规格： | 50μg | 产品价格： | ￥880.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
功能
Serine/threonine-protein kinase involved in various processes such as neuronal proliferation, differentiation, migration and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK10/JNK3. In turn, MAPK10/JNK3 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity. Plays regulatory roles in the signaling pathways during neuronal apoptosis. Phosphorylates the neuronal microtubule regulator STMN2. Acts in the regulation of the beta-amyloid precursor protei/PP signaling during neuronal differentiation by phosphorylating APP. Participates also in neurite growth in spiral ganglion neurons. Phosphorylates the CLOCK-ARNTL/BMAL1 heterodimer and plays a role in the photic regulation of the circadian clock (PubMed:22441692).风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验JNK3-Mediated Apoptotic Cell Death in Primary Dopaminergic Neurons
primary mesencephalic dopaminergic neurons and examining the activation of c-Jun N-terminal protein Kinase (JNK) in these cultures. We utilized immunocytochemistry and computerized analysis to quantify the number of surviving dopaminergic neurons and JNK
运用Cell Based Elisa检测信号通路蛋白和磷酸化蛋白
也有类似产品。在我们这里先介绍两种目的蛋白的检测实验，we presented data on two targets: p38 mitogen activated protein kinase (MAPK) and stress-activated protein kinase/Jun-terminal kinase (SAPK/JNK)其中P38 MAPK和JNK是参与到separate MAP kinase cascade pathways and function mainly
. Y., and Yao, S. Q. (2002) Antibody-based fluorescence detection of kinase activity on a peptide array. Bioorg.Med. Chem. Lett. 1 2 , 2085-2088. 7. Fukunaga, R. and Hunter, T. (1997) M N K 1 , a n e w M A P kinase-activated protein kinase
技术资料暂无技术资料 索取技术资料
