POLR3E抗体POLR3E兔多抗抗体DNA-directe
d RNA polymerase III 80 kDa polypeptide antibody抗体POLR3E Antibody, Biotin conjugated抗体- ￥880 - 1320
- CUSABIO
- CN
- CSB-PA868333LD01HU
- 2025年07月11日
- ELISA
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant Human DNA-directed RNA polymerase III subunit RPC5 protein (1-260AA)
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
Biotin
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
Q9NVU0
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA
- 浓度：
>95%,Protein G purified
- 靶点：
POLR3E
- 抗体英文名：
POLR3E Antibody, Biotin conjugated
- 抗体名：
POLR3E antibody;KIAA1452 antibody;DNA-directed RNA polymerase III subunit RPC5 antibody;RNA polymerase III subunit C5 antibody;DNA-directed RNA polymerase III 80 kDa polypeptide antibody
- 规格：
100μg/50μg
| 规格： | 100μg | 产品价格： | ￥1320.0 |
|---|---|---|---|
| 规格： | 50μg | 产品价格： | ￥880.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
功能
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Preparation of Cytotoxic Antibody-Toxin Conjugates
(1 ). Ricin and abrin are protein toxins consisting of two different polypeptide subunits, the A and B chains, which are of similar size (between 30 and 34 kDa) and are joined by a single disulfide bond. The A chain is a ribosome-inactivating protein (RIP
Inducing RNAi with siRNA Cocktails Generated by RNase III
per microgram of RNA for 1 hour at 37°C, to generate siRNA cocktails for each target gene. After a 1 hour digestion with RNase III, the long dsRNAs were reduced to fragments Silencing by RNase III Digested dsRNA. We next analyzed the silencing
.I. Preparation of Template DNA 1.Design two oligos for your gene of interest.Each should incorporate a 5' T7 RNA polymerase binding site, resulting in a PCR product of approximately 700 bp.2.T7 RNA polymerase binding site: TTA ATA CGA CTC ACT ATA GGG AGG
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