APOBEC3C抗体APOBEC3C兔多抗抗体Probabl
e DNA dC->dU-editing enzyme APOBEC-3C antibody抗体APOBEC3C Antibody抗体- ￥440 - 1320
- CUSABIO
- CN
- CSB-PA889097ESR1HU
- 2025年07月08日
- ELISA, IHC; Recommended dilution: IHC:1:20-1:200
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant Human DNA dC->dU-editing enzyme APOBEC-3C protein (1-190AA)
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
Q9NRW3
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA, IHC; Recommended dilution: IHC:1:20-1:200
- 浓度：
>95%,Antigen Affinity Purified
- 靶点：
APOBEC3C
- 抗体英文名：
APOBEC3C Antibody
- 抗体名：
Probable DNA dC->dU-editing enzyme APOBEC-3C antibody
- 规格：
100μl/50μl/20μl
| 规格： | 100μl | 产品价格： | ￥1320.0 |
|---|---|---|---|
| 规格： | 50μl | 产品价格： | ￥880.0 |
| 规格： | 20μl | 产品价格： | ￥440.0 |
保存缓冲液
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.功能
DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity against simian immunodeficiency virus (SIV), hepatitis B virus (HBV), herpes simplex virus 1 (HHV-1) and Epstein-Barr virus (EBV) and may inhibit the mobility of LTR and non-LTR retrotransposons. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Rapid Extraction of High Quality DNA from Whole Blood Stored at 4ºC for Long Period
gel 6% and Digestion of DNA with EcoR1 restriction enzyme are given in Figure 1. The yields of the DNA samples ranged from 1.0 to 3.0 µg from 500µl blood that was stored at 4ºC for one year. This amount of DNA is enough to conduct 200 to 300 PCR
诺奖得主 Jennifer 最新研究：CRISPR/Cas12c 无需切割 DNA 就可实现基因沉默，抵御病毒入侵
是有待回答的问题。 2022 年 6 月 2 日，诺奖得主 Jennifer A. Doudna 及其团队在 Molecular Cell 发表了题为 A naturally DNase-free CRISPR-Cas12c enzyme silences gene expression 的研究文章，发现 Cas12c 是一种 RNA 引导的 DNA 结合酶，它不切割靶 DNA，而是通过 crRNA 介导的相互作用与靶 DNA 结合，并可以通过识别噬菌体必需基因来保护细菌免受噬菌体的感染。 图片
Restriction Enzyme Digestion of DNA
.3.Incubate at the appropriate temperature (usually 37E C) for 1 to 2 hours.4.Run a small aliquot on a gel to check for digestion.5.If the DNA is to be used for another manipulation, heat inactivate the enzyme (if it is heat labile) at 70 E C for 15 min
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