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KCTD6抗体KCTD6兔多抗抗体potassium cha

nnel tetramerization domain containing 6 antibody抗体KCTD6 Antibody, Biotin conjugated抗体
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  • ¥880 - 1320
  • CUSABIO已认证
  • CN
  • CSB-PA822756LD01HU
  • 2025年07月09日
  • ELISA
  • Rabbit
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Recombinant Human BTB/POZ domain-containing protein KCTD6 protein (1-237AA)

    • 亚型

      IgG

    • 形态

      Liquid

    • 保存条件

      Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.

    • 克隆性

      Polyclonal

    • 标记物

      Biotin

    • 适应物种

      Human

    • 保质期

      6个月

    • 抗原来源

      Homo sapiens (Human)

    • 目录编号

      Q8NC69

    • 级别

    • 库存

      200

    • 供应商

      武汉华美生物工程有限公司

    • 宿主

      Rabbit

    • 应用范围

      ELISA

    • 浓度

      >95%,Protein G purified

    • 靶点

      KCTD6

    • 抗体英文名

      KCTD6 Antibody, Biotin conjugated

    • 抗体名

      BTB/POZ domain-containing protein KCTD6 antibody;KCASH3 antibody;kctd6 antibody;KCTD6_HUMAN antibody;MGC27385 antibody;potassium channel tetramerization domain containing 6 antibody

    • 规格

      100μg/50μg

    规格:100μg产品价格:¥1320.0
    规格:50μg产品价格:¥880.0

    保存缓冲液

    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

    功能

    Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1; the function seems to depend on KCTD11:KCTD6 oligomerization. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142). Involved in regulating protein levels of ANK1 isoform Mu17 probably implicating CUL3-dependent proteasomal degradation (PubMed:22573887).

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    图标文献和实验
    该产品被引用文献
    更多文献信息可以查看cusabio官网
    相关实验
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    • Introduction of human 14-3-3 proteins

      terminus of GPIb-alpha,as indicated by antibody inhibition and direct binding of 14-3-3zeta to synthetic GPIb-alpha cytoplasmic domain peptides.The 14-3-3zeta binds to recombinant wild type GPIb-IX but not to the GPIb-alpha mutants lacking C-terminal

    • Rational Design and Evaluation of FRET Experiments to Measure Protein Proximities in Cells

      Figure 17.9.4 Sampling size and the resolving power of antibody‐mediated FRET. (A ) Diagram of a model IgG molecule bound to an antigen on the membrane surface (left). The Fc and each Fab domain are modeled as a cylinder of diameter 30 Å

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    文献支持
    KCTD6抗体KCTD6兔多抗抗体potassium channel tetramerization domain containing 6 antibody抗体KCTD6 Antibody, Biotin conjugated抗体
    ¥880 - 1320