KCTD6抗体KCTD6兔多抗抗体potassium cha
nnel tetramerization domain containing 6 antibody抗体KCTD6 Antibody, Biotin conjugated抗体- ￥880 - 1320
- CUSABIO
- CN
- CSB-PA822756LD01HU
- 2025年07月09日
- ELISA
- Rabbit
- Human
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- 文献和实验
- 技术资料
- 免疫原：
Recombinant Human BTB/POZ domain-containing protein KCTD6 protein (1-237AA)
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
Biotin
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
Q8NC69
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA
- 浓度：
>95%,Protein G purified
- 靶点：
KCTD6
- 抗体英文名：
KCTD6 Antibody, Biotin conjugated
- 抗体名：
BTB/POZ domain-containing protein KCTD6 antibody;KCASH3 antibody;kctd6 antibody;KCTD6_HUMAN antibody;MGC27385 antibody;potassium channel tetramerization domain containing 6 antibody
- 规格：
100μg/50μg
| 规格： | 100μg | 产品价格： | ￥1320.0 |
|---|---|---|---|
| 规格： | 50μg | 产品价格： | ￥880.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
功能
Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1; the function seems to depend on KCTD11:KCTD6 oligomerization. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142). Involved in regulating protein levels of ANK1 isoform Mu17 probably implicating CUL3-dependent proteasomal degradation (PubMed:22573887).风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验secondary antibody review -- data from 99 publications
cytometry used as a control to detect cell responses targeted antigen 7 Alexa Fluor 488 7 Cy3 8 goat IgG Alexa Fluor 488 1:2000 detect antibody binding in human embryonic kidney 293T cells Invitrogen 9 donkey
Introduction of human 14-3-3 proteins
terminus of GPIb-alpha,as indicated by antibody inhibition and direct binding of 14-3-3zeta to synthetic GPIb-alpha cytoplasmic domain peptides.The 14-3-3zeta binds to recombinant wild type GPIb-IX but not to the GPIb-alpha mutants lacking C-terminal
Rational Design and Evaluation of FRET Experiments to Measure Protein Proximities in Cells
Figure 17.9.4 Sampling size and the resolving power of antibody‐mediated FRET. (A ) Diagram of a model IgG molecule bound to an antigen on the membrane surface (left). The Fc and each Fab domain are modeled as a cylinder of diameter 30 Å
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